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      Clinical effects associated with five-year retinal nerve fiber layer thinning in multiple sclerosis.

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          Abstract

          Neurodegenerative changes in multiple sclerosis (MS) are associated with long-term disability progression (DP). Optical coherence tomography (OCT) measures may be used to monitor DP.

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          Author and article information

          Journal
          J Neurol Sci
          Journal of the neurological sciences
          Elsevier BV
          1878-5883
          0022-510X
          Aug 15 2021
          : 427
          Affiliations
          [1 ] Jacobs Comprehensive MS Treatment and Research Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA. Electronic address: djakimovski@bnac.net.
          [2 ] Jacobs Comprehensive MS Treatment and Research Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; Center for Biomedical Imaging at Clinical Translational Science Institute, University at Buffalo, State University of New York, Buffalo, NY, USA.
          [3 ] Jacobs Comprehensive MS Treatment and Research Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
          Article
          S0022-510X(21)00246-X
          10.1016/j.jns.2021.117552
          34175775
          ca8df108-e602-4a4f-a481-989d8ad924a7
          History

          Multiple sclerosis,OCT,Optic neuritis,RNFL,Disability progression

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