Effects of statin therapy on coronary artery plaque volume and high-risk plaque morphology in HIV-infected patients with subclinical atherosclerosis: a randomised, double-blind, placebo-controlled trial.

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Abstract

HIV-infected patients have a high risk of myocardial infarction. We aimed to assess the ability of statin treatment to reduce arterial inflammation and achieve regression of coronary atherosclerosis in this population.

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Journal

Journal ID (iso-abbrev): Lancet HIV

Title: The lancet. HIV

ISSN (Electronic): 2352-3018

ISSN (Print): 2352-3018

Publication date (Electronic): Feb 2015

Volume: 2

Issue: 2

Affiliations

[1 ] Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

[2 ] Cardiovascular Imaging Section, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

[3 ] Division of Cardiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA USA.

[4 ] Division of Infectious Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

[5 ] Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

[6 ] Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: sgrinspoon@mgh.harvard.edu.

Article

Publisher Item ID: S2352-3018(14)00032-0 Mid ID: NIHMS772176

DOI: 10.1016/S2352-3018(14)00032-0

PMC ID: 4820828

PubMed ID: 26424461

SO-VID: c8fe731f-73ec-4586-a072-83a2a3d30fde

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