Successful treatment of active ankylosing spondylitis with the anti-tumor necrosis factor alpha monoclonal antibody infliximab.

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Abstract

Tumor necrosis factor alpha (TNFalpha) has been detected in sacroiliac joint biopsy specimens from patients with spondylarthropathy. The present open pilot study was undertaken to test the efficacy of the anti-TNFalpha monoclonal antibody infliximab in the treatment of active ankylosing spondylitis (AS).

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Journal

Journal ID (iso-abbrev): Arthritis Rheum

Title: Arthritis and rheumatism

Publisher: Wiley

ISSN: 0004-3591

ISSN (Print): 0004-3591

Publication date (Electronic): Jun 2000

Volume: 43

Issue: 6

Affiliations

[1 ] Benjamin Franklin Hospital, Free University Berlin, Germany.

Article

DOI: 10.1002/1529-0131(200006)43:6<1346::AID-ANR18>3.0.CO;2-E

PubMed ID: 10857793

SO-VID: c8c9e9cb-0fc3-4f6d-98eb-8e8bfb2e0664

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