Feasibility and safety of hyperthermic intraperitoneal chemotherapy using 5-fluorouracil combined with cisplatin and mitomycin C in patients undergoing gastrectomy for advanced gastric cancer.

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Abstract

We conducted a dose-finding study for 5-fluorouracil (5-FU) administered with cisplatin (CDDP) and mitomycin C (MMC) to find an improved regimen for hyperthermic intraperitoneal chemotherapy (HIPEC) for advanced gastric cancer (GC).

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Author and article information

Journal

Journal ID (iso-abbrev): J Surg Oncol

Title: Journal of surgical oncology

Publisher: Wiley

ISSN (Electronic): 1096-9098

ISSN (Print): 0022-4790

Publication date (Electronic): Dec 2017

Volume: 116

Issue: 8

Affiliations

[1 ] Department of Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.

[2 ] Cancer Center, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.

[3 ] Department of Surgery, Kusatsu General Hospital, Kusatsu, Shiga, Japan.

[4 ] Department of Surgery, Hino Memorial Hospital, Hino-cho, Gamou-gun, Shiga, Japan.

[5 ] Department of Surgery, Nagahama Red Cross Hospital, Nagahama, Shiga, Japan.

[6 ] Biomedical Innovation Center, Shiga University of Medical Science, Otsu, Shiga, Japan.

Article

DOI: 10.1002/jso.24771

PubMed ID: 28743181

SO-VID: c8160956-07a4-45d6-9f32-5ecc21512f3e

History

Keywords: HIPEC,surgery,5-FU,phase I study,peritoneal dissemination

Data availability:

Keywords: HIPEC, surgery, 5-FU, phase I study, peritoneal dissemination

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