Nonlinear Association Between Cerebrospinal Fluid and Florbetapir F-18 β-Amyloid Measures Across the Spectrum of Alzheimer Disease.

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Abstract

Cerebrospinal fluid (CSF) and positron emission tomographic (PET) amyloid biomarkers have been proposed for the detection of Alzheimer disease (AD) pathology in living patients and for the tracking of longitudinal changes, but the relation between biomarkers needs further study.

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Journal

Journal ID (iso-abbrev): JAMA Neurol

Title: JAMA neurology

ISSN (Electronic): 2168-6157

ISSN (Print): 2168-6149

Publication date (Electronic): May 2015

Volume: 72

Issue: 5

Affiliations

[1 ] Institute on Aging, Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

[2 ] Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia.

[3 ] Helen Wills Neuroscience Institute, University of California, Berkeley.

[4 ] Center for Alzheimer's Care, Imaging and Research, Department of Neurology, University of Utah, Salt Lake City.

[5 ] Mayo Clinic College of Medicine, Rochester, Minnesota.

[6 ] Center for Imaging of Neurodegenerative Diseases, Department of Radiology, San Francisco VA Medical Center/University of California, San Francisco.

Article

Publisher Item ID: 2212147

DOI: 10.1001/jamaneurol.2014.4829

PubMed ID: 25822737

SO-VID: c4ddc25d-9ced-4f0e-aa6e-cd61cabc7537

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