An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy

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Abstract

ABSTRACT Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment.

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Author and article information

Contributors

MARIANA Q. MESQUITA: Role: ND

CRISTINA J. DIAS: Role: ND

SARA GAMELAS: Role: ND

MARGARIDA FARDILHA: Role: ND

MARIA G.P.M.S. NEVES: Role: ND

MARIA AMPARO F. FAUSTINO: Role: ND

Journal

Journal ID (publisher-id): aabc

Title: Anais da Academia Brasileira de Ciências

Abbreviated Title: An. Acad. Bras. Ciênc.

Publisher: Academia Brasileira de Ciências (Rio de Janeiro, RJ, Brazil )

ISSN (Print): 0001-3765

ISSN (Electronic): 1678-2690

Publication date (Print and electronic): 2018

Volume: 90

Issue: 1 suppl 2

Pages: 1101-1130

Affiliations

[2] Aveiro orgnameUniversidade de Aveiro orgdiv1Department of Biomedical Sciences Portugal

[1] Aveiro orgnameUniversidade de Aveiro orgdiv1Department of Chemistry and QOPNA Portugal

Article

Publisher ID: S0001-37652018000301101

DOI: 10.1590/0001-3765201720170800

PubMed ID: 29873674

SO-VID: c3d020f5-6619-4b15-94a1-3b4832a4d3f9

License:

This work is licensed under a Creative Commons Attribution 4.0 International License.

History

Date received : 09 October 2017

Date accepted : 19 November 2017

Page count

Figures: 0, Tables: 0, Equations: 0, References: 191, Pages: 30

Product

SciELO Brazil

Keywords: Gold nanoparticles,Polymeric micelles,Photodynamic therapy,Drug delivery,Liposomes,Silica nanoparticles

Data availability:

Keywords: Gold nanoparticles, Polymeric micelles, Photodynamic therapy, Drug delivery, Liposomes, Silica nanoparticles

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