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      Overall Survival Results of a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Routine Cancer Treatment

      research-article
      , MD, MSc 1 , 2 , , , MS 1 , , PhD 4 , , MD 3 , , MD 3 , , MD 5 , , MD, MPH 6 , 2
      JAMA
      American Medical Association

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          Abstract

          This study assesses overall survival associated with electronic patient-reported symptom monitoring vs usual care during routine cancer treatment.

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          Author and article information

          Journal
          JAMA
          JAMA
          JAMA
          JAMA
          American Medical Association
          0098-7484
          1538-3598
          4 June 2017
          11 July 2017
          4 December 2017
          : 318
          : 2
          : 197-198
          Affiliations
          [1 ]Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill
          [2 ]Associate Editor, JAMA
          [3 ]Memorial Sloan Kettering Cancer Center, New York, New York
          [4 ]Mayo Clinic, Scottsdale, Arizona
          [5 ]American Society of Clinical Oncology, Alexandria, Virginia
          [6 ]Dana-Farber/Harvard Cancer Center, Boston, Massachusetts
          Author notes
          Article Information
          Corresponding Author: Ethan Basch, MD, Cancer Outcomes Research Program, Lineberger Comprehensive Cancer Center, University of North Carolina, 170 Manning Dr, CB# 7305, Chapel Hill, NC 27599-7305 ( ebasch@ 123456med.unc.edu ).
          Accepted for Publication: May 22, 2017.
          Published Online: June 4, 2017. doi:10.1001/jama.2017.7156
          Author Contributions: Dr Basch had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
          Concept and design: Basch, Dueck, Scher, Schrag.
          Acquisition, analysis, or interpretation of data: All authors.
          Drafting of the manuscript: Basch, Deal, Scher.
          Critical revision of the manuscript for important intellectual content: All authors.
          Statistical analysis: Deal, Dueck, Schrag.
          Obtained funding: Kris.
          Administrative, technical, or material support: Basch, Scher, Kris, Hudis, Schrag.
          Supervision: Hudis, Schrag.
          Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported. Dr Scher reports receiving personal fees from Astellas, BIND Pharmaceuticals, Clovis Oncology, Merck, Roche, Asterias Biotherapeutics, WIRB-Copernicus Group, and Sanofi Aventis; nonfinancial support from Ferring Pharmaceuticals, Janssen Research and Development, Medivation, and Takeda Millennium; and grants from Medivation, Janssen, Illumina, and Innocrin Pharma. Dr Kris reports receiving personal fees from Genetech/Roche, AstraZeneca, and ARIAD. No other disclosures were reported.
          Funding/Support: This trial was funded by the Conquer Cancer Foundation of the American Society of Clinical Oncology.
          Role of the Funder/Sponsor: The Conquer Cancer Foundation had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
          Trial Registration: clinicaltrials.gov: NCT00578006
          Disclaimer: Drs Basch and Schrag, both JAMA associate editors, were not involved in the review of or decision to publish this letter.
          Meeting Presentation: This article was presented at the annual American Society of Clinical Oncology meeting; June 4, 2017; Chicago, Illinois.
          Additional Contributions: We thank Lauren Rogak, MA, Laura Sit, MA, Thomas Atkinson, PhD, Dorothy Dulko, RN, PhD, and Paul Sabbatini, MD (all from Memorial Sloan Kettering Cancer Center); Allison Barz, MD (Children’s Hospital of Pennsylvania); and Antonia Bennett, PhD (University of North Carolina), for their collaboration in the conduct and analysis of this study. No one received compensation for their contribution.
          Article
          PMC5817466 PMC5817466 5817466 jld170018
          10.1001/jama.2017.7156
          5817466
          28586821
          c2a31f74-380c-4903-90ca-6089974f24d4
          Copyright 2017 American Medical Association. All Rights Reserved.
          History
          : 11 May 2017
          : 19 May 2017
          : 22 May 2017
          Funding
          Funded by: Conquer Cancer Foundation
          Categories
          Letter
          Letters
          Research Letter
          Online First

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