Article Information
Corresponding Author: Ethan Basch, MD, Cancer Outcomes Research Program, Lineberger Comprehensive Cancer
Center, University of North Carolina, 170 Manning Dr, CB# 7305, Chapel Hill, NC 27599-7305
(
ebasch@
123456med.unc.edu
).
Accepted for Publication: May 22, 2017.
Published Online: June 4, 2017. doi:10.1001/jama.2017.7156
Author Contributions: Dr Basch had full access to all of the data in the study and takes responsibility
for the integrity of the data and the accuracy of the data analysis.
Concept and design: Basch, Dueck, Scher, Schrag.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Basch, Deal, Scher.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Deal, Dueck, Schrag.
Administrative, technical, or material support: Basch, Scher, Kris, Hudis, Schrag.
Supervision: Hudis, Schrag.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential
Conflicts of Interest and none were reported. Dr Scher reports receiving personal
fees from Astellas, BIND Pharmaceuticals, Clovis Oncology, Merck, Roche, Asterias
Biotherapeutics, WIRB-Copernicus Group, and Sanofi Aventis; nonfinancial support from
Ferring Pharmaceuticals, Janssen Research and Development, Medivation, and Takeda
Millennium; and grants from Medivation, Janssen, Illumina, and Innocrin Pharma. Dr
Kris reports receiving personal fees from Genetech/Roche, AstraZeneca, and ARIAD.
No other disclosures were reported.
Funding/Support: This trial was funded by the
Conquer Cancer Foundation of the American Society of Clinical Oncology.
Role of the Funder/Sponsor: The Conquer Cancer Foundation had no role in the design and conduct of the study;
collection, management, analysis, and interpretation of the data; preparation, review,
or approval of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: Drs Basch and Schrag, both
JAMA associate editors, were not involved in the review of or decision to publish this
letter.
Meeting Presentation: This article was presented at the annual American Society of Clinical Oncology meeting;
June 4, 2017; Chicago, Illinois.
Additional Contributions: We thank Lauren Rogak, MA, Laura Sit, MA, Thomas Atkinson, PhD, Dorothy Dulko, RN,
PhD, and Paul Sabbatini, MD (all from Memorial Sloan Kettering Cancer Center); Allison
Barz, MD (Children’s Hospital of Pennsylvania); and Antonia Bennett, PhD (University
of North Carolina), for their collaboration in the conduct and analysis of this study.
No one received compensation for their contribution.