Gestational organophosphate ester exposure and preschool attention-deficit/hyperactivity disorder in the Norwegian Mother, Father, and Child cohort study.

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Abstract

Attention-deficit/hyperactivity-disorder (ADHD) is a leading neurodevelopmental disorder in children worldwide; however, few modifiable risk factors have been identified. Organophosphate esters (OPEs) are ubiquitous chemical compounds that are increasingly prevalent as a replacement for other regulated chemicals. Current research has linked OPEs to neurodevelopmental deficits. The purpose of this study was to assess gestational OPE exposure on clinically-assessed ADHD in children at age 3 years.

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Journal

Journal ID (iso-abbrev): Int J Hyg Environ Health

Title: International journal of hygiene and environmental health

Publisher: Elsevier BV

ISSN (Electronic): 1618-131X

ISSN (Print): 1438-4639

Publication date (Electronic): Mar 2023

Volume: 248

Affiliations

[1 ] Department of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA. Electronic address: amber_hall@brown.edu.

[2 ] Department of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.

[3 ] Department of Public Health Sciences, School of Medicine, Queen's University, Kingston, Ontario, Canada.

[4 ] Department of Environmental Health and Engineering, Johns Hopkins University, Baltimore, MD, USA.

[5 ] Department of Child Health and Development, Division of Mental and Physical Health, Norwegian Institute of Public Health, Oslo, Norway.

[6 ] Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Mental Disorders, Division of Mental and Physical Health, Norwegian Institute of Public Health, Oslo, Norway.

[7 ] Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

[8 ] Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

[9 ] Department of Food Safety, Division of Climate and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.

Article

Mid ID: NIHMS1853331 Publisher Item ID: S1438-4639(22)00161-4

DOI: 10.1016/j.ijheh.2022.114078

PMC ID: 9898152

PubMed ID: 36455478

SO-VID: c285e6c0-c2f4-4557-adf4-58a1e3958c8a

History

Keywords: Organophosphate ester,ADHD,Flame retardant,MoBa,Neurodevelopment,Preschool

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Keywords: Organophosphate ester, ADHD, Flame retardant, MoBa, Neurodevelopment, Preschool

Gestational organophosphate ester exposure and preschool attention-deficit/hyperactivity disorder in the Norwegian Mother, Father, and Child cohort study.

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