[1
]ISNI 0000 0001 0670 2351, GRID grid.59734.3c, The Mindich Child Health & Development Institute and the Department of Genetics &
Genomic Sciences, , Icahn School of Medicine at Mount Sinai, ; New York, NY 10029 USA
[2
]ISNI 0000 0001 0670 2351, GRID grid.59734.3c, Graduate School of Biomedical Sciences, , Icahn School of Medicine at Mount Sinai, ; New York, NY 10029 USA
[3
]ISNI 0000 0001 0670 2351, GRID grid.59734.3c, The Seaver Autism Center for Research and Treatment, , Icahn School of Medicine at Mount Sinai, ; New York, NY 10029 USA
[4
]ISNI 0000 0001 2108 5881, GRID grid.418922.4, School of Theoretical and Applied Sciences, , Ramapo College of New Jersey, ; Mahwah, NJ 07430 USA
[5
]ISNI 0000 0001 0670 2351, GRID grid.59734.3c, Department of Genetics and Genomic Sciences, , Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount
Sinai, ; New York, NY 10029 USA
[6
]ISNI 0000 0001 0670 2351, GRID grid.59734.3c, Department of Psychiatry, , Icahn School of Medicine at Mount Sinai, ; New York, NY 10029 USA
[7
]ISNI 0000 0001 2159 175X, GRID grid.10328.38, ICVS/3B’s PT Government Associate Laboratory, Life and Health Sciences Research Institute,
School of Medicine, , University of Minho, ; Braga/Guimarães, 4710-057 Portugal
[8
]ISNI 0000000122931605, GRID grid.5590.9, Radboud University Medical Center, Department of Human Genetics, , Donders Institute for Brain, Cognition and Behaviour, ; Nijmegen, 6500 HB The Netherlands
[9
]ISNI 0000 0001 0670 2351, GRID grid.59734.3c, The Division of Tics, OCD and Related Disorders, Department of Psychiatry, and Mindich
Child Health and Development Institute, , Icahn School of Medicine at Mount Sinai, ; New York, NY 10029 USA
[10
]ISNI 0000 0001 0670 2351, GRID grid.59734.3c, The Friedman Brain Institute, , Icahn School of Medicine at Mount Sinai, ; New York, NY 10029 USA
[11
]Center for Medical Genetics Dr. Jacinto Magalhães, Porto Hospital Center, Porto, 4050-106
Portugal
[12
]Maastricht University Medical Center, Department of Clinical Genetics, GROW School
for Oncology and Developmental Biology, Maastricht, 6229 HX The Netherlands
[13
]ISNI 0000 0001 0670 2351, GRID grid.59734.3c, Department of Pediatrics, , Icahn School of Medicine at Mount Sinai, ; New York, NY 10029 USA
[14
]GRID grid.428467.b, Cardiogenetic Program, GeneDx, Inc., ; Gaithersburg, MD 20877 USA
License:
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License,
which permits use, sharing, adaptation, distribution and reproduction in any medium
or format, as long as you give appropriate credit to the original author(s) and the
source, provide a link to the Creative Commons license, and indicate if changes were
made. The images or other third party material in this article are included in the
article’s Creative Commons license, unless indicated otherwise in a credit line to
the material. If material is not included in the article’s Creative Commons license
and your intended use is not permitted by statutory regulation or exceeds the permitted
use, you will need to obtain permission directly from the copyright holder. To view
a copy of this license, visit
http://creativecommons.org/licenses/by/4.0/.