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Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016–2030
Chris Estes ,
Quentin M. Anstee ,
Maria Teresa Arias-Loste ,
Heike Bantel ,
Stefano Bellentani ,
Joan Caballeria ,
Massimo Colombo ,
Antonio Craxi ,
Javier Crespo ,
Christopher P. Day ,
Yuichiro Eguchi ,
Andreas Geier ,
Loreta A. Kondili ,
Daniela C. Kroy ,
Jeffrey V. Lazarus ,
Rohit Loomba ,
Michael P. Manns ,
Giulio Marchesini ,
Atsushi Nakajima ,
Francesco Negro ,
Salvatore Petta ,
Vlad Ratziu ,
Manuel Romero-Gomez ,
Arun Sanyal ,
Jörn M. Schattenberg ,
Frank Tacke ,
Junko Tanaka ,
Christian Trautwein ,
Lai Wei ,
Stefan Zeuzem ,
Homie Razavi
October 2018
October 2018
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Abstract
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)
are increasingly a cause of cirrhosis and hepatocellular carcinoma globally. This
burden is expected to increase as epidemics of obesity, diabetes and metabolic syndrome
continue to grow. The goal of this analysis was to use a Markov model to forecast
NAFLD disease burden using currently available data.