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      Predictors of positive patient-reported outcomes from ‘Early Intervention in Psychosis’: a national cross-sectional study

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          Abstract

          Background

          The components of care delivered by Early Intervention in Psychosis (EIP) services vary, but the impact on patient experience is unknown.

          Objective

          To investigate associations between components of care provided by EIP services in England and patient-reported outcomes.

          Methods

          2374 patients from EIP services in England were surveyed during the National Clinical Audit of Psychosis. Participants were asked about the care they received, and completed the ‘Patient Global Impressions’ Scale (rating whether their mental health had improved), and ‘Friends and Family Test’ (rating whether they would recommend their service). Information about service structure was obtained from service providers. We analysed associations between outcomes and components of care using multilevel regression.

          Findings

          The majority of participants were likely to recommend the treatment they had received (89.8%), and felt that their mental health had improved (89.0%). Participants from services where care coordinators had larger case loads were less likely to recommend their care. Participants were more likely to recommend their care if they had been offered cognitive behavioural therapy for psychosis, family therapy or targeted interventions for carers. Participants were more likely to report that their mental health had improved if they had been offered cognitive behavioural therapy for psychosis or targeted interventions for carers.

          Conclusions

          Specific components of EIP care were associated with improved patient reported outcomes. Psychosocial interventions and carer support may be particularly important in optimising outcomes for patients.

          Clinical implications

          These findings emphasise the need for small case load sizes and comprehensive packages of treatment in EIP services.

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          Most cited references25

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          The one number you need to grow.

          Companies spend lots of time and money on complex tools to assess customer satisfaction. But they're measuring the wrong thing. The best predictor of top-line growth can usually be captured in a single survey question: Would you recommend this company to a friend? This finding is based on two years of research in which a variety of survey questions were tested by linking the responses with actual customer behavior--purchasing patterns and referrals--and ultimately with company growth. Surprisingly, the most effective question wasn't about customer satisfaction or even loyalty per se. In most of the industries studied, the percentage of customers enthusiastic enough about a company to refer it to a friend or colleague directly correlated with growth rates among competitors. Willingness to talk up a company or product to friends, family, and colleagues is one of the best indicators of loyalty because of the customer's sacrifice in making the recommendation. When customers act as references, they do more than indicate they've received good economic value from a company; they put their own reputations on the line. And they will risk their reputations only if they feel intense loyalty. The findings point to a new, simpler approach to customer research, one directly linked to a company's results. By substituting a single question--blunt tool though it may appear to be--for the complex black box of the customer satisfaction survey, companies can actually put consumer survey results to use and focus employees on the task of stimulating growth.
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            Schizophrenia.

            Schizophrenia, characterised by psychotic symptoms and in many cases social and occupational decline, remains an aetiological and therapeutic challenge. Contrary to popular belief, the disorder is modestly more common in men than in women. Nor is the outcome uniformly poor. A division of symptoms into positive, negative, and disorganisation syndromes is supported by factor analysis. Catatonic symptoms are not specific to schizophrenia and so-called first rank symptoms are no longer considered diagnostically important. Cognitive impairment is now recognised as a further clinical feature of the disorder. Lateral ventricular enlargement and brain volume reductions of around 2% are established findings. Brain functional changes occur in different subregions of the frontal cortex and might ultimately be understandable in terms of disturbed interaction among large-scale brain networks. Neurochemical disturbance, involving dopamine function and glutamatergic N-methyl-D-aspartate receptor function, is supported by indirect and direct evidence. The genetic contribution to schizophrenia is now recognised to be largely polygenic. Birth and early life factors also have an important aetiological role. The mainstay of treatment remains dopamine receptor-blocking drugs; a psychological intervention, cognitive behavioural therapy, has relatively small effects on symptoms. The idea that schizophrenia is better regarded as the extreme end of a continuum of psychotic symptoms is currently influential. Other areas of debate include cannabis and childhood adversity as causative factors, whether there is progressive brain change after onset, and the long-term success of early intervention initiatives.
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              Size of burden of schizophrenia and psychotic disorders.

              Schizophrenia is a severe mental disorder characterised by fundamental disturbances in thinking, perception and emotions. More than 100 years of research have not been able to fully resolve the puzzle that schizophrenia represents. Even if schizophrenia is not a very frequent disease, it is among the most burdensome and costly illnesses worldwide. It usually starts in young adulthood. Life expectancy is reduced by approximately 10 years, mostly as a consequence of suicide. Even if the course of the illness today is considered more favourable than it was originally described, it is still only a minority of those affected, who fully recover. The cumulative lifetime risk for men and women is similar, although it is higher for men in the age group younger than 40 years. According to the Global Burden of Disease Study, schizophrenia causes a high degree of disability, which accounts for 1.1% of the total DALYs (disability-adjusted life years) and 2.8% of YLDs (years lived with disability). In the World Health Report [The WHO World Health Report: new understanding, new hope, 2001. Geneva], schizophrenia is listed as the 8th leading cause of DALYs worldwide in the age group 15-44 years. In addition to the direct burden, there is considerable burden on the relatives who care for the sufferers. The treatment goals for the moment are to identify the illness as early as possible, treat the symptoms, provide skills to patients and their families, maintain the improvement over a period of time, prevent relapses and reintegrate the ill persons into the community so that they can lead as normal a life as possible.
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                Author and article information

                Journal
                BMJ Ment Health
                BMJ Ment Health
                bmjment
                ebmh
                BMJ Mental Health
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                2755-9734
                2023
                4 August 2023
                : 26
                : 1
                : e300716
                Affiliations
                [1 ] departmentDepartment of Brain Sciences , Ringgold_4615Imperial College London , London, UK
                [2 ] departmentCollege Centre for Quality Improvement , Ringgold_9725Royal College of Psychiatrists , London, UK
                [3 ] departmentDepartment of Psychological Sciences , Ringgold_4591University of Liverpool , Liverpool, UK
                [4 ] departmentDepartment of Psychiatry , Ringgold_6396University of Oxford , Oxford, UK
                [5 ] departmentDepartment of Psychosis Studies , Ringgold_4616King's College London , London, UK
                [6 ] departmentDepartment of Clinical Neuroscience , Karolinska Institutet , Stockholm, Sweden
                [7 ] departmentDepartment of Psychology , Ringgold_5289Manchester Metropolitan University , Manchester, UK
                [8 ] departmentSchool of Public Health , Ringgold_4615Imperial College London , London, UK
                Author notes
                [Correspondence to ] Dr Ryan Williams, Department of Brain Sciences, Imperial College London, London W12 0NN, Greater London, UK; ryan.williams2@ 123456nhs.net
                Author information
                http://orcid.org/0000-0001-8486-4903
                Article
                bmjment-2023-300716
                10.1136/bmjment-2023-300716
                10577709
                37541700
                bc30b903-d272-479c-a1ad-24e0946ed9b9
                © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See:  https://creativecommons.org/licenses/by/4.0/.

                History
                : 21 March 2023
                : 05 July 2023
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100000272, National Institute for Health and Care Research;
                Award ID: NIHR302320
                Categories
                Adult Mental Health
                1506
                Custom metadata
                unlocked

                schizophrenia & psychotic disorders,adult psychiatry

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