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Patterns of initial disease recurrence after resection of gallbladder carcinoma and hilar cholangiocarcinoma: implications for adjuvant therapeutic strategies.
William R Jarnagin
1 ,
Leyo Ruo ,
Sarah A Little ,
David Klimstra ,
Michael D'Angelica ,
Ronald P DeMatteo ,
Raquel Wagman ,
Leslie H Blumgart ,
Yuman Fong
Oct 15 2003
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Abstract
Current approaches to adjuvant treatment after resection of gallbladder carcinoma (GBCA) and hilar cholangiocarcinoma (HCCA) are based on an incomplete understanding of the recurrence patterns of these diseases. Through an in-depth analysis of the sites of initial recurrence after resection of GBCA and HCCA, the current study aimed to highlight differences in the biology of these tumors and to provide further insight for adjuvant therapeutic strategies.