For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
24
views
29
references
 Top references
cited by
3
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      247
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Radiation injury is a potentially serious complication to fluoroscopically-guided complex interventions

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Radiation-induced injury to skin is an infrequent but potentially serious complication to complex fluoroscopically-guided interventional procedures. Due to a lack of experience with such injuries, the medical community has found fluoroscopically-induced injuries difficult to diagnose. Injuries have occurred globally in many countries. Serious injuries most frequently occur on the back but have also occurred on the neck, buttocks and anterior of the chest. Severities of injuries range from skin rashes and epilation to necrosis of the skin and its underlying structures. This article reviews the characteristics of these injuries and some actions that can be taken to reduce their likelihood or seriousness.

          Related collections

          Most cited references29

          • Record: found
          • Abstract: not found
          • Article: not found

          Skin injuries from fluoroscopically guided procedures: part 1, characteristics of radiation injury.

          T Koenig, Bret A Mettler, Eric Wolff … (2001)
          Article 0 comments Cited 57 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Skin injuries from fluoroscopically guided procedures: part 2, review of 73 cases and recommendations for minimizing dose delivered to patient.

            Caroline S. Wagner, T Koenig, F Mettler (2001)
            Article 0 comments Cited 33 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Diabetes mellitus: a predictor for late radiation morbidity.

              G Hanks, D Herold, Cathleen Hanlon (1999)
              Given the high frequency of diabetes, as well as prostate cancer in the elderly population, we sought to determine whether diabetic patients treated with three-dimensional conformal external-beam radiotherapy (3DCRT) had an increased risk of late gastrointestinal (GI) or genitourinary (GU) complications. Nine-hundred forty-four prostate cancer patients were treated between April 1989 and October 1996 using 3DCRT. Median patient age was 69 years (range 48-89), median center of prostate dose was 7211 cGy (range 6211-8074) and median follow-up was 36 months (range 2-99). Patients were evaluated every 6 months with digital rectal examinations, serum PSAs and symptom questionnaires. Radiation morbidity was quantified using Radiation Therapy Oncology Group (RTOG) and modified Late Effects Normal Tissue Task Force (LENT) scales. Patients with a preexisting history of either Type I or Type II diabetes mellitus were coded as diabetics. One hundred twenty-one patients had diabetes (13% of total). Rates of acute morbidity did not differ between diabetics and nondiabetics; however, diabetics experienced significantly more late grade 2 GI toxicity (28% vs. 17%, p = 0.011) and late grade 2 GU toxicity (14% vs. 6%, p = 0.001). There was a trend toward increased late grade 3 and 4 GI complications in diabetics, but not for late grade 3 and 4 GU complications; however, the total number of recorded events for these categories was small. Examining the onset of late toxicity, diabetics developed GU complications earlier than nondiabetics (median: 10 months vs. 24 months, p = 0.02). Considering age, dose, rectal blocking, field size, and history of diabetes in a stepwise multivariate regression model for late grade 2 GI toxicity, dose (p = 0.0001), diabetes (p = 0.0110), and rectal blocking (p = 0.0163) emerged independently predictive for complications. For late grade 2 GU toxicity, only the presence of diabetes remained independently significant (p = 0.0014). Diabetes mellitus is common in the elderly prostate cancer population. Diabetics are at a significant risk for the development of late grade 2 GI and GU complications after external-beam radiotherapy for prostate cancer. While diabetes, radiation dose, and rectal blocking predict for late GI complications, only the presence of diabetes influences late GU morbidity. Physicians may consider treatment modifications for diabetic patients, particularly those patients wishing to enter dose-escalation studies. Further study of the relationship between diabetes and late radiation complications is needed.
              Article 0 comments Cited 28 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Biomed Imaging Interv J
                Journal ID (publisher-id): biij
                Title: Biomedical Imaging and Intervention Journal
                Publisher: Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Malaysia
                ISSN (Electronic): 1823-5530
                Publication date (Electronic): 01 April 2007
                Publication date Collection: Apr-Jun 2007
                Volume: 3
                Issue: 2
                Electronic Location Identifier: e22
                Affiliations
                Department of Diagnostic and Interventional Imaging, The University of Texas Medical School at Houston, Houston, Texas, USA.
                Author notes
                [* ] Corresponding author. Present address: Department of Diagnostic and Interventional Imaging, The University of Texas Medical School at Houston, Houston, Texas, USA. E-mail: louis.k.wagner@ 123456uth.tmc.edu (Louis Wagner).
                Article
                DOI: 10.2349/biij.3.2.e22
                PMC ID: 3097662
                PubMed ID: 21614271
                SO-VID: ba4047e7-5f0e-4948-b215-ff83309fa5fe
                Copyright © © 2007 Biomedical Imaging and Intervention Journal
                License:

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 07 January 2007
                Date accepted : 03 April 2007
                Categories
                Subject: Review Article

                ScienceOpen disciplines: Radiology & Imaging
                Data availability:
                ScienceOpen disciplines: Radiology & Imaging

                Comments

                Comment on this article

                scite_

                Similar content247

                See all similar

                Cited by3

                See all cited by