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      Computer Aided Diagnostic Support System for Skin Cancer: A Review of Techniques and Algorithms

      review-article
      * ,
      International Journal of Biomedical Imaging
      Hindawi Publishing Corporation

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          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Image-based computer aided diagnosis systems have significant potential for screening and early detection of malignant melanoma. We review the state of the art in these systems and examine current practices, problems, and prospects of image acquisition, pre-processing, segmentation, feature extraction and selection, and classification of dermoscopic images. This paper reports statistics and results from the most important implementations reported to date. We compared the performance of several classifiers specifically developed for skin lesion diagnosis and discussed the corresponding findings. Whenever available, indication of various conditions that affect the technique's performance is reported. We suggest a framework for comparative assessment of skin cancer diagnostic models and review the results based on these models. The deficiencies in some of the existing studies are highlighted and suggestions for future research are provided.

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          Most cited references152

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          Extreme learning machine: Theory and applications

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            Using mutual information for selecting features in supervised neural net learning.

            R Battiti (1994)
            This paper investigates the application of the mutual information criterion to evaluate a set of candidate features and to select an informative subset to be used as input data for a neural network classifier. Because the mutual information measures arbitrary dependencies between random variables, it is suitable for assessing the "information content" of features in complex classification tasks, where methods bases on linear relations (like the correlation) are prone to mistakes. The fact that the mutual information is independent of the coordinates chosen permits a robust estimation. Nonetheless, the use of the mutual information for tasks characterized by high input dimensionality requires suitable approximations because of the prohibitive demands on computation and samples. An algorithm is proposed that is based on a "greedy" selection of the features and that takes both the mutual information with respect to the output class and with respect to the already-selected features into account. Finally the results of a series of experiments are discussed.
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              Regression modelling strategies for improved prognostic prediction

              Regression models such as the Cox proportional hazards model have had increasing use in modelling and estimating the prognosis of patients with a variety of diseases. Many applications involve a large number of variables to be modelled using a relatively small patient sample. Problems of overfitting and of identifying important covariates are exacerbated in analysing prognosis because the accuracy of a model is more a function of the number of events than of the sample size. We used a general index of predictive discrimination to measure the ability of a model developed on training samples of varying sizes to predict survival in an independent test sample of patients suspected of having coronary artery disease. We compared three methods of model fitting: (1) standard 'step-up' variable selection, (2) incomplete principal components regression, and (3) Cox model regression after developing clinical indices from variable clusters. We found regression using principal components to offer superior predictions in the test sample, whereas regression using indices offers easily interpretable models nearly as good as the principal components models. Standard variable selection has a number of deficiencies.
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                Author and article information

                Journal
                Int J Biomed Imaging
                Int J Biomed Imaging
                IJBI
                International Journal of Biomedical Imaging
                Hindawi Publishing Corporation
                1687-4188
                1687-4196
                2013
                23 December 2013
                : 2013
                : 323268
                Affiliations
                School of Electrical, Mechanical and Mechatronic Engineering, University of Technology, Broadway Ultimo, Sydney, NSW 2007, Australia
                Author notes

                Academic Editor: Michael W. Vannier

                Article
                10.1155/2013/323268
                3885227
                24575126
                ba2fcef5-c82d-431e-bb9b-6adb171ba46e
                Copyright © 2013 A. Masood and A. Ali Al-Jumaily.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 27 August 2013
                : 30 October 2013
                Categories
                Review Article

                Radiology & Imaging
                Radiology & Imaging

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