Liraglutide With Metformin Therapy Ameliorates Hepatic Steatosis and Liver Injury in a Mouse Model of Non-alcoholic Steatohepatitis.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Non-alcoholic fatty liver disease is a major cause of liver-related morbidity and mortality. Metformin is a widely used medication and may have additional benefits beyond glycemic control. Liraglutide, a novel treatment for diabetes and obesity, also has beneficial effects on non-alcoholic steatohepatitis (NASH). Metformin and liraglutide have both benefited NASH treatment. However, no study has reported the effects of combination therapy with liraglutide and metformin on NASH.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): In Vivo

Title: In vivo (Athens, Greece)

Publisher: Anticancer Research USA Inc.

ISSN (Electronic): 1791-7549

ISSN (Print): 0258-851X

Publication date (Electronic): 2023

Volume: 37

Issue: 3

Affiliations

[1 ] Department of Pharmacy, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, R.O.C.

[2 ] Graduate Institute of Clinical Pharmacy, College of Medicine, Tzu Chi University, Hualien, Taiwan, R.O.C.

[3 ] Holistic Education Center, Tzu Chi University of Science and Technology, Hualien, Taiwan, R.O.C.

[4 ] Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.

[5 ] School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan, R.O.C.

[6 ] China Medical University Children's Hospital, Taichung, Taiwan, R.O.C.

[7 ] Department of Medical Genetics, China Medical University Hospital, Taichung, Taiwan, R.O.C.

[8 ] Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan, R.O.C.

[9 ] Laboratory Animal Service Center, China Medical University, Taichung, Taiwan, R.O.C.

[10 ] Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan, R.O.C.; jaisingyang@gmail.com.

[11 ] Division of Plastic and Reconstructive Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.; chiou70202@gmail.com.

[12 ] Department of Surgery, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, R.O.C.

Article

Publisher Item ID: 37/3/1037

DOI: 10.21873/invivo.13178

PMC ID: 10188031

PubMed ID: 37103096

SO-VID: b97db640-a01f-4140-b686-31fd3505f4c5

History

Keywords: liver injury,MCD diet,Liraglutide,non-alcoholic steatohepatitis,C57BL/6JNarl mouse model,metformin

Data availability:

Keywords: liver injury, MCD diet, Liraglutide, non-alcoholic steatohepatitis, C57BL/6JNarl mouse model, metformin

Liraglutide With Metformin Therapy Ameliorates Hepatic Steatosis and Liver Injury in a Mouse Model of Non-alcoholic Steatohepatitis.

Read this article at

Abstract

Related collections

Neuropharmacology and Therapy

Author and article information

Journal

Affiliations

Article

History

Comments

Comment on this article

Similar content 956

Cited by 2