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      Growth arrest lines and intra-epiphyseal silhouettes: a case series

      case-report
      1 , 4 , 2 , 3 ,
      BMC Research Notes
      BioMed Central
      Growth arrest lines, Orthopaedics, Physis

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          Abstract

          Background

          Growth arrest lines can develop within the skeleton after physiological stress or trauma. They are usually evident on radiographs as transverse lines in the metaphyses and have been used in fields from palaeontology to orthopaedics. This report consists of three cases, two of which describe growth arrest lines in an intra-epiphyseal site hitherto rarely documented, and a third demonstrating their clinical application.

          Case presentation

          Case 1 describes a 9-year-old who suffered a knee hyperflexion injury requiring anterior cruciate ligament and posterior cruciate ligament reattachments. She subsequently developed a marked distal femoral intra-epiphyseal arrest silhouette, as well as metaphyseal arrest lines in the femur, tibia and fibula. Case 2 describes an 8-year-old who sustained a tibial spine fracture and underwent open reduction and internal fixation. Subsequent imaging shows a further example of femoral intra-epiphyseal arrest silhouette as well as tibia and fibula metaphyseal arrest lines. Case 3 describes a 10-year-old who sustained a distal tibia fracture which was managed with open reduction and internal fixation. Subsequently the metaphyseal growth arrest line was parallel to the physis, suggesting no growth arrest (a danger with such a fracture).

          Conclusion

          This case series describes two examples of rarely described intra-epiphyseal growth arrest silhouettes and demonstrates the usefulness of arrest lines when assessing for growth plate damage.

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          Most cited references10

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          Harris lines revisited: prevalence, comorbidities, and possible etiologies.

          The occurrence of transverse radiopaque lines in long bones-Harris lines (HLs)-is correlated with episodes of temporary arrest of longitudinal growth and has been used as an indicator of health and nutritional status of modern and historical populations. However, the interpretation of HLs as a stress indicator remains debatable. The aim of this article is to evaluate the perspectives and the limitations of HLs analyses and to examine their reliability as a stress indicator. The study was conducted on 241 tibiae from a medieval Swiss skeletal material and was carried out using a standardized, semiautomated HL detection and analysis tool developed by the authors. We compared four different age-at-formation estimation methods and analyzed the correlation of HL occurrence to life expectancy, mean-age-at-death, stature, tibia length, and metabolic disorders as expressed by linear enamel hypoplasia and hypothyroidism. The evaluation of the age-at-formation estimation methods showed statistical significant differences. Therefore, a mathematical framework for the conversion between the methods has been developed. Remodeling had eliminated about half of the HLs formed during adolescence, and a further half of the remaining ones during early adulthood, whereas no association between the aforementioned conditions and HL prevalence could be determined. The peaks of high HL frequency among various populations were found to parallel normal growth spurts and growth hormone secretion. We suggest a reconsideration of HLs as more of a result of normal growth and growth spurts, rather than a pure outcome of nutritional or pathologic stress. Copyright © 2011 Wiley-Liss, Inc.
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            THE IMPRINTING OF NUTRITIONAL DISTURBANCES ON THE GROWING BONE.

            E A PARK (1964)
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              The acrophysis: a unifying concept for understanding enchondral bone growth and its disorders. II. Abnormal growth.

              In order to discuss and illustrate the effects common to normal and abnormal enchondral bone at the physes and at all other growth plates of the developing child, the term "acrophysis" was proposed. Acrophyses include the growth plates of secondary growth centers including carpals and tarsals and apophyses, and the growth plates at the nonphyseal ends of small tubular bones. Abnormalities at acrophyseal sites are analogous to those at the physeal growth plates and their metaphyses. For example, changes relating to the zone of provisional calcification (ZPC) are often important to the demonstration of such similarities. Lead lines were an early example of the concept of analogy from abnormality due to physeal and to acrophyseal disturbance. The ZPC is a key factor in understanding patterns of rickets and its healing. Examples (including hypothyroidism, scurvy and other osteoporosis, Ollier disease, achondroplasia, and osteopetrosis, as well as the family of frostbite, Kashin-Beck disease, and rat bite fever) illustrate the acrophysis principle and in turn their manifestations are explained by that principle.
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                Author and article information

                Journal
                BMC Res Notes
                BMC Res Notes
                BMC Research Notes
                BioMed Central
                1756-0500
                2014
                10 January 2014
                : 7
                : 27
                Affiliations
                [1 ]The Western Infirmary, Glasgow G11 6NT, UK
                [2 ]Radiology Department, Royal Hospital for Sick Children, Glasgow, Yorkhill G3 8SJ, UK
                [3 ]Glasgow University/Orthopaedic Department, Royal Hospital for Sick Children, Glasgow, Yorkhill G3 8SJ, UK
                [4 ]University of Glasgow, School of Medicine, Glasgow G12 8QQ, UK
                Article
                1756-0500-7-27
                10.1186/1756-0500-7-27
                3927262
                24410952
                b9627bcf-0fd1-4954-9e39-fb58ec32499d
                Copyright © 2014 Kennedy et al.; licensee BioMed Central Ltd.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 14 October 2013
                : 30 December 2013
                Categories
                Case Report

                Medicine
                growth arrest lines,orthopaedics,physis
                Medicine
                growth arrest lines, orthopaedics, physis

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