Medication correction of the main clinical symptoms of generalized periodontitis in patients with different blood groups

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Abstract

The article presents the results of treatment of 106 patients with generalized periodontitis (GP) depending on blood type. We determined the effectiveness of treatment by the frequency of detection of the main clinical symptoms (dental plaque, tartar, bleeding, tenderness, gingival hyperemia, serous-purulent discharge, periodontal pockets, pathological tooth mobility, radiological changes in the alveolar membranes) of GP. As a result of applying our proposed therapy, it was found that on day 3–5 after treatment only in patients with blood group 0 (I) of the main group the number of patients with clinical symptoms of GP was significantly less than in the control group (13.58±3.39% of patients vs. 25.69±6.42% of patients, p<0.01, respectively). At 1 month after treatment, there was a significant difference in the presence of clinical symptoms of GP in patients with blood group 0 (I) of the main and control groups (6.17±1.53% vs. 21.58±5.40%, p<0.05, respectively) and with blood group B (III) (8.33±2.08% vs. 22.22±5.56%, p<0.05, respectively). In patients with A (II) and AB (IV) blood groups, the number of patients with symptoms of GP in the study groups did not differ from each other during this follow-up period, p>0.05. After 6–12 months of study, in patients with GP, regardless of blood group, the number of patients in the main group with clinical symptoms of GP was significantly lower than in the control group, p<0.01. The improvement of clinical symptoms in patients with generalized periodontitis indicates a positive effect on the periodontal tissue the medicines we have prescribed.

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Global burden of severe periodontitis in 1990-2010: a systematic review and meta-regression.

N Kassebaum, E Bernabé, M. Dahiya … (2014)

We aimed to consolidate all epidemiologic data about severe periodontitis (SP) and, subsequently, to generate internally consistent prevalence and incidence estimates for all countries, 20 age groups, and both sexes for 1990 and 2010. The systematic search of the literature yielded 6,394 unique citations. After screening titles and abstracts, we excluded 5,881 citations as clearly not relevant to this systematic review, leaving 513 for full-text review. A further 441 publications were excluded following the validity assessment. A total of 72 studies, including 291,170 individuals aged 15 yr or older in 37 countries, were included in the metaregression based on modeling resources of the Global Burden of Disease 2010 Study. SP was the sixth-most prevalent condition in the world. Between 1990 and 2010, the global age-standardized prevalence of SP was static at 11.2% (95% uncertainty interval: 10.4%-11.9% in 1990 and 10.5%-12.0% in 2010). The age-standardized incidence of SP in 2010 was 701 cases per 100,000 person-years (95% uncertainty interval: 599-823), a nonsignificant increase from the 1990 incidence of SP. Prevalence increased gradually with age, showing a steep increase between the third and fourth decades of life that was driven by a peak in incidence at around 38 yr of age. There were considerable variations in prevalence and incidence between regions and countries. Policy makers need to be aware of a predictable increasing burden of SP due to the growing world population associated with an increasing life expectancy and a significant decrease in the prevalence of total tooth loss throughout the world from 1990 to 2010.

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A new classification scheme for periodontal and peri-implant diseases and conditions - Introduction and key changes from the 1999 classification

Jack G Caton, Gary Armitage, Tord Berglundh … (2018)

A classification scheme for periodontal and peri-implant diseases and conditions is necessary for clinicians to properly diagnose and treat patients as well as for scientists to investigate etiology, pathogenesis, natural history, and treatment of the diseases and conditions. This paper summarizes the proceedings of the World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions. The workshop was co-sponsored by the American Academy of Periodontology (AAP) and the European Federation of Periodontology (EFP) and included expert participants from all over the world. Planning for the conference, which was held in Chicago on November 9 to 11, 2017, began in early 2015. An organizing committee from the AAP and EFP commissioned 19 review papers and four consensus reports covering relevant areas in periodontology and implant dentistry. The authors were charged with updating the 1999 classification of periodontal diseases and conditions and developing a similar scheme for peri-implant diseases and conditions. Reviewers and workgroups were also asked to establish pertinent case definitions and to provide diagnostic criteria to aid clinicians in the use of the new classification. All findings and recommendations of the workshop were agreed to by consensus. This introductory paper presents an overview for the new classification of periodontal and peri-implant diseases and conditions, along with a condensed scheme for each of four workgroup sections, but readers are directed to the pertinent consensus reports and review papers for a thorough discussion of the rationale, criteria, and interpretation of the proposed classification. Changes to the 1999 classification are highlighted and discussed. Although the intent of the workshop was to base classification on the strongest available scientific evidence, lower level evidence and expert opinion were inevitably used whenever sufficient research data were unavailable. The scope of this workshop was to align and update the classification scheme to the current understanding of periodontal and peri-implant diseases and conditions. This introductory overview presents the schematic tables for the new classification of periodontal and peri-implant diseases and conditions and briefly highlights changes made to the 1999 classification. It cannot present the wealth of information included in the reviews, case definition papers, and consensus reports that has guided the development of the new classification, and reference to the consensus and case definition papers is necessary to provide a thorough understanding of its use for either case management or scientific investigation. Therefore, it is strongly recommended that the reader use this overview as an introduction to these subjects. Accessing this publication online will allow the reader to use the links in this overview and the tables to view the source papers (Table ).

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Staging and grading of periodontitis: Framework and proposal of a new classification and case definition.

Maurizio Tonetti, Henry Greenwell, Kenneth S Kornman (2018)

Authors were assigned the task to develop case definitions for periodontitis in the context of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. The aim of this manuscript is to review evidence and rationale for a revision of the current classification, to provide a framework for case definition that fully implicates state-of-the-art knowledge and can be adapted as new evidence emerges, and to suggest a case definition system that can be implemented in clinical practice, research and epidemiologic surveillance.