Procyanidins and sensory nutrition; do procyanidins modulate homeostasis via astringent taste receptors?

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ABSTRACT

Long-term intake of procyanidins has been suggested to reduce the risk of cardiovascular disease, dementia, and sensory function decline associated with aging. However, most of the ingested procyanidins are not absorbed and are excreted in the feces, so the mechanism of their beneficial impact is unknown. Procyanidins are the components of astringency in plant foods and their stimulation appears to be directly transmitted to the central nervous system via sensory nerves. Recent attention has been focused on the taste receptors expressed in the extra-oral gastrointestinal tract may regulate homeostasis via the neuroendocrine system. In this paper, we have reviewed recent findings on the relationship between the astringency of procyanidins and their bioregulatory effects.

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Most cited references 43

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Author and article information

Contributors

Naomi Osakabe: (View ORCID Profile)

Journal

Title: Bioscience, Biotechnology, and Biochemistry

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1347-6947

Publication date Created: November 01 2023

Publication date (Electronic): November 01 2023

Article

DOI: 10.1093/bbb/zbad154

PubMed ID: 37930827

SO-VID: b6b41363-193c-412e-9cb6-f571b2d8196d

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https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model

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