There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Two papers, one in Nature (Jones et al., 2006) and the other in the Journal of Clinical Investigation (Verma et al., 2006) show that Nck adaptor proteins connect phosphorylated nephrin with actin polymerization in podocyte foot processes, structures important for slit-diaphragm formation in the kidney. Their results further our understanding of podocyte development and repair in glomerular disease.

Related collections

Author and article information

Journal

PubMed ID:: 16630808

DOI:: 10.1016/j.cell.2006.04.002

ScienceOpen disciplines: Chemistry

Keywords: Actins,metabolism,Adaptor Proteins, Signal Transducing,Animals,Cells, Cultured,Cytoskeleton,Kidney Glomerulus,cytology,pathology,Membrane Proteins,Mice,Oncogene Proteins,Podocytes

Data availability:

ScienceOpen disciplines: Chemistry

Comments

Comment on this article

scite_

Smart Citations

Citing PublicationsSupportingMentioningContrasting

View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.