Estimated GFR and the Effect of Intensive Blood Pressure Lowering After Acute Intracerebral Hemorrhage.

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Abstract

The kidney-brain interaction has been a topic of growing interest. Past studies of the effect of kidney function on intracerebral hemorrhage (ICH) outcomes have yielded inconsistent findings. Although the second, main phase of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2) suggests the effectiveness of early intensive blood pressure (BP) lowering in improving functional recovery after ICH, the balance of potential benefits and harms of this treatment in those with decreased kidney function remains uncertain.

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Journal

Journal ID (iso-abbrev): Am. J. Kidney Dis.

Title: American journal of kidney diseases : the official journal of the National Kidney Foundation

Publisher: Elsevier BV

ISSN (Electronic): 1523-6838

ISSN (Print): 0272-6386

Publication date (Electronic): Jul 2016

Volume: 68

Issue: 1

Affiliations

[1 ] The George Institute for Global Health, Sydney, Australia; Sydney Medical School, University of Sydney, Sydney, Australia.

[2 ] The George Institute for Global Health, Sydney, Australia.

[3 ] The George Institute for Global Health, Sydney, Australia; Sydney Medical School, University of Sydney, Sydney, Australia; Center for Epidemiologic Research in Asia, Shiga University of Medical Sciences, Otsu, Japan.

[4 ] The George Institute for Global Health, Sydney, Australia; Sydney Medical School, University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia.

[5 ] The George Institute for Global Health, Sydney, Australia; Department of Neurology, The Second Affiliated Hospital of Suzhou University, Suzhou, China.

[6 ] The George Institute for Global Health, Sydney, Australia; Sydney Medical School, University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia. Electronic address: canderson@georgeinstitute.org.au.

Article

Publisher Item ID: S0272-6386(16)00147-5

DOI: 10.1053/j.ajkd.2016.01.020

PubMed ID: 26948991

SO-VID: b53f2c0d-e6aa-4c7a-a2d3-7732e4b22708

History

Keywords: INTERACT2,Kidney function,cerebral hemorrhage,cerebrovascular disease,chronic kidney disease (CKD),dialysis,estimated glomerular filtration rate (eGFR),hemodialysis,intensive blood pressure lowering treatment,intracerebral hemorrhage (ICH),stroke,systolic blood pressure

Estimated GFR and the Effect of Intensive Blood Pressure Lowering After Acute Intracerebral Hemorrhage.

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