Glucokinase activators AZD6370 and AZD1656 do not affect the central counterregulatory response to hypoglycemia in healthy males.

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Abstract

Glucokinase is expressed in the hypothalamus, but effects of glucokinase activators (GKAs) on counterregulatory responses to hypoglycemia are unknown.

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Journal

Journal ID (iso-abbrev): J. Clin. Endocrinol. Metab.

Title: The Journal of clinical endocrinology and metabolism

Publisher: The Endocrine Society

ISSN (Electronic): 1945-7197

ISSN (Print): 0021-972X

Publication date (Electronic): Sep 2012

Volume: 97

Issue: 9

Affiliations

[1 ] Division of Research and Development, AstraZeneca, 431 83 Mölndal, Sweden. ensio.norjavaara@astrazeneca.com

Article

Publisher Item ID: jc.2012-1496

DOI: 10.1210/jc.2012-1496

PubMed ID: 22723318

SO-VID: b508eb43-f378-49a0-8db6-85fc0e1ebe16

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