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      Tissue engineering for bone regeneration and osseointegration in the oral cavity.

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          Abstract

          The focus of this review is to summarize recent advances on regenerative technologies (scaffolding matrices, cell/gene therapy and biologic drug delivery) to promote reconstruction of tooth and dental implant-associated bone defects.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Dent Mater
          Title: Dental materials : official publication of the Academy of Dental Materials
          Publisher: Elsevier BV
          ISSN (Electronic): 1879-0097
          ISSN (Print): 0109-5641
          Publication date (Electronic): Apr 2015
          Volume: 31
          Issue: 4
          Affiliations
          [1 ] Department of Biomedical Engineering, College of Engineering, University of Michigan, Ann Arbor, 1101 Beal Avenue, Ann Arbor, MI 48109, USA. Electronic address: spilipch@umich.edu.
          [2 ] Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, 1011 N. University Avenue, Ann Arbor, MI 48109, USA. Electronic address: aplonka@umich.edu.
          [3 ] Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, 1011 N. University Avenue, Ann Arbor, MI 48109, USA. Electronic address: amonjec@umich.edu.
          [4 ] Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, 1011 N. University Avenue, Ann Arbor, MI 48109, USA. Electronic address: adtaut@umich.edu.
          [5 ] Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, 1011 N. University Avenue, Ann Arbor, MI 48109, USA. Electronic address: alelanis@umich.edu.
          [6 ] Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, 1011 N. University Avenue, Ann Arbor, MI 48109, USA. Electronic address: benkang@umich.edu.
          [7 ] Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, 1011 N. University Avenue, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, College of Engineering, University of Michigan, Ann Arbor, 1101 Beal Avenue, Ann Arbor, MI 48109, USA. Electronic address: wgiannob@umich.edu.
          Article
          Publisher Item ID: S0109-5641(15)00020-2 Mid ID: NIHMS665532
          DOI: 10.1016/j.dental.2015.01.006
          PMC ID: 4376374
          PubMed ID: 25701146
          SO-VID: b3e96bc6-87ec-4a28-a0d1-4f546803f777
          History

          Keywords: Bone tissue engineering,Cell therapy,Gene therapy,Growth factor delivery,Periodontal regeneration,Scaffolds
          Data availability:
          Keywords: Bone tissue engineering, Cell therapy, Gene therapy, Growth factor delivery, Periodontal regeneration, Scaffolds

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