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      SIRT1 signalling protects mouse oocytes against oxidative stress and is deregulated during aging.

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          Abstract

          Is SIRT1 involved in the oxidative stress (OS) response in mouse oocytes?

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          Author and article information

          Journal
          Hum. Reprod.
          Human reproduction (Oxford, England)
          1460-2350
          0268-1161
          Sep 2014
          : 29
          : 9
          Affiliations
          [1 ] Department of Life, Health and Environmental Sciences, University of L'Aquila, Via Vetoio, 67100 L'Aquila, Italy.
          [2 ] Servizio di PMA, Azienda Ospedaliera Cannizzaro, Catania, Italy.
          [3 ] Dipartimento Gian Filippo Ingrassia, Sezione di Biologia, Genetica, Genomica Cellulare e Molecolare Giovanni Sichel, Università degli Studi di Catania, Catania, Italy.
          [4 ] Department of Life, Health and Environmental Sciences, University of L'Aquila, Via Vetoio, 67100 L'Aquila, Italy Infertility Service, San Salvatore Hospital, Via Vetoio, 67100 L'Aquila, Italy carla.tatone@univaq.it.
          Article
          deu160
          10.1093/humrep/deu160
          24963165
          b1576fa3-ede8-4ff6-8589-345579dd6736
          © The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
          History

          SIRT1,miRNA,oocyte aging,oxidative stress,sirtuins
          SIRT1, miRNA, oocyte aging, oxidative stress, sirtuins

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