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Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: a functional MRI study.
S L Rauch
1 ,
P J Whalen ,
L M Shin ,
S C McInerney ,
M L Macklin ,
N B Lasko ,
S P Orr ,
R K Pitman
May 01 2000
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Abstract
Converging lines of evidence have implicated the amygdala in the pathophysiology of posttraumatic stress disorder (PTSD). We previously developed a method for measuring automatic amygdala responses to general threat-related stimuli; in conjunction with functional magnetic resonance imaging, we used a passive viewing task involving masked presentations of human facial stimuli.