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      Effect of Cataract Type and Severity on Visual Acuity and Contrast Sensitivity

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          Abstract

          Purpose

          To determine the effect of cataract type and severity in eyes with pure types of age-related lens opacities on visual acuity (VA) and contrast sensitivity in the presence and absence of glare conditions.

          Methods

          Sixty patients with senile cataracts aged 40 years or older with no other ocular pathologies were evaluated for VA and contrast sensitivity with and without glare. Lens opacities were classified according to the Lens Opacities Classification System (LOCS) III. VA was measured using the Snellen chart. Contrast sensitivity was measured with the Vector Vision CSV-1000E chart in the presence and absence of glare by calculating the area under log contrast sensitivity (log CS) function (AULCSF).

          Results

          Cataracts were posterior subcapsular in 26 eyes, cortical in 19 eyes and nuclear in 15 eyes. VA significantly decreased with increasing cataract severity and there was significant loss of contrast sensitivity at all spatial frequencies with increasing cataract severity. AULCSF significantly decreased with increasing cataract severity in the presence and absence of glare conditions. Contrast sensitivity was significantly reduced at high spatial frequency (18 cpd) in cortical cataracts in the presence of glare in day light and at low spatial frequency (3 cpd) in night light.

          Conclusion

          Increased cataract severity is strongly associated with a decrease in both VA and AULCSF. Contrast sensitivity scores may offer additional information over standard VA tests in patients with early age-related cataracts.

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          Most cited references35

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          Compensation comparison method for assessment of retinal straylight.

          Presently, no instrument or method exists that is generally accepted for routine clinical assessment of (functional) retinal straylight. Yet retinal straylight is the cause of major patient complaints, such as hindrance from glare and loss of contrast. It results from disturbances in the optical media that increase light-scattering over angles of 1 degrees to 90 degrees . Its assessment would help to decide whether to perform surgery for (early) cataract and would help in the evaluation of corneal or vitreal turbidity. The psychophysical technique of the "direct compensation" method was adapted to make it suitable for routine clinical assessment. In the new approach, called "compensation comparison, " the central test field is subdivided into two half fields: one with and one without counterphase compensation light. The subject's task is a forced-choice comparison between the two half fields, to decide which half flickers more strongly. A theoretical form for the respective psychometric function was defined and experimentally verified in a laboratory experiment involving seven subjects, with and without artificially increased light scattering. The method was applied in a separate multicenter study. Its reliability was additionally tested with a commercial implement (C-Quant; Oculus Optikgeräte, Wetzlar-Dutenhofen, Germany). A repeated-measures SD of 0.07 log units was achieved, to be compared with differences in the young normal population of 0.4 log units and an increase with healthy aging by 0.5 log units at 80 years and by 1.0 or more log units with (early) cataract or corneal disturbances. Reliability was further found to be high when using the commercial version of the The compensation comparison method for measuring retinal straylight is suited for clinical use to diagnose patients with complaints caused by large angle light scattering in the eye such as early cataract.
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            Test-retest reliability of the CSV-1000 contrast test and its relationship to glaucoma therapy.

            To determine the relationship between changes in contrast sensitivity, if any, after glaucoma therapy and the test-retest reliability of the CSV-1000 contrast sensitivity test. Patients with primary open angle glaucoma (N = 16) were retrospectively evaluated to determine changes in visual function, as measured by contrast sensitivity, after beta-blocker therapy. A control group (N = 24) of normally sighted patients was tested and retested on contrast sensitivity. For the control group, the coefficients of repeatability (95% confidence interval for test-retest variability [COR]) were calculated for each spatial frequency. The CORs were compared to the changes in vision found after therapy in the patients with glaucoma. The group with glaucoma showed a significant improvement (P < .01) in contrast sensitivity at all spatial frequencies. The test-retest variance for normals, as measured by the COR, was smaller than the mean differences in contrast sensitivity before and after therapy at all spatial frequencies, expect 18 cyc/deg. Visual function in patients with glaucoma, as measured by contrast sensitivity, does improve after beta-blocker therapy. Further, the CSV-1000 is a clinically reliable tool for monitoring these changes.
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              Contrast sensitivity testing: a more complete assessment of vision.

              Contrast sensitivity testing is a powerful tool for determining the capability of the visual system to process spatial and temporal information about the everyday objects we see. The current gold standard in the assessment of vision, visual acuity, provides only a limited amount of information, obtained under artificial conditions. Contrast sensitivity testing measures a range of visual performance under real-life conditions. It measures the least amount of contrast needed to detect a visual stimulus and gives us a more complete quantitization of patients' visual capabilities. Many instances in which losses in contrast sensitivity were detected when visual acuity (one point on the contrast sensitivity function) was normal have been reported. These include amblyopia, neuro-ophthalmology, retina, anterior segment disease, and glaucoma. Therefore, contrast sensitivity testing enables the clinician to diagnose selective deficits in visual processing at an earlier stage than is possible with conventional testing methods.
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                Author and article information

                Journal
                J Ophthalmic Vis Res
                JOVR
                Journal of Ophthalmic & Vision Research
                Ophthalmic Research Center
                2008-2010
                2008-322X
                January 2011
                : 6
                : 1
                : 26-31
                Affiliations
                [1 ]Department of Optometry, Mashhad University of Medical Sciences, Mashhad, Iran
                [2 ]Eye Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran
                [3 ]Department of Optometry, Tehran University of Medical Sciences, Tehran, Iran
                [4 ]Depatment of Biostatistics, Mashhad University of Medical Sciences, Mashhad, Iran
                Author notes
                Correspondence to: Javad Heravian Shandiz, MSc, PhD. Department of Optometry, Paramedical Faculty, Mashhad University of Medical Sciences, Felestin Sq., Mashhad, Iran; Tel: +98 511 7610111, Fax: +98 511 7628088; e-mail: heravianj@ 123456mums.ac.ir
                Article
                jovr-6-1-026
                3306069
                22454703
                af3b0b52-26bc-4ec8-a922-b5ebfbd3f0a5
                Copyright @ 2011

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 26 August 2010
                : 13 November 2010
                Categories
                Original Article

                Ophthalmology & Optometry
                visual acuity,age-related cataract,contrast sensitivity,glare sensitivity

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