Novel 10-kHz High-frequency Therapy (HF10 Therapy) Is Superior to Traditional Low-frequency Spinal Cord Stimulation for the Treatment of Chronic Back and Leg Pain: The SENZA-RCT Randomized Controlled Trial.

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Abstract

Current treatments for chronic pain have limited effectiveness and commonly known side effects. Given the prevalence and burden of intractable pain, additional therapeutic approaches are desired. Spinal cord stimulation (SCS) delivered at 10 kHz (as in HF10 therapy) may provide pain relief without the paresthesias typical of traditional low-frequency SCS. The objective of this randomized, parallel-arm, noninferiority study was to compare long-term safety and efficacy of SCS therapies in patients with back and leg pain.

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Journal

Journal ID (iso-abbrev): Anesthesiology

Title: Anesthesiology

ISSN (Electronic): 1528-1175

ISSN (Print): 0003-3022

Publication date (Electronic): Oct 2015

Volume: 123

Issue: 4

Affiliations

[1 ] From the Center for Clinical Research and Carolina's Pain Institute at Brookstown, Wake Forest Baptist Health, Winston-Salem, North Carolina (L.K.); Swedish Pain Center, Seattle, Washington (C.Y., T.Y.); The Pain Center of Arizona and HOPE Research Institute, Phoenix, Arizona (M.W.D.A.H.B.); Clinical and Regulatory Affairs, Nevro Corp., Menlo Park, California (B.E.G.); Millennium Pain Center, Bloomington, Illinois (R.V., R. Benyamin); Advanced Pain Therapy, PLLC, Hattiesburg, Mississippi (B.T.S.); IPM Medical Group, Inc., Walnut Creek, California (K.A.); Pain Consultants of Oregon, Eugene, Oregon (D.M.M.); Coastal Orthopedics and Pain Medicine, Bradenton, Florida (L.L.B., R. Bundschu); Comprehensive Pain and Rehabilitation, Pascagoula, Mississippi (T.L.Y.); and Houston Pain Associates, Houston, Texas (A.W.B.).

Article

DOI: 10.1097/ALN.0000000000000774

PubMed ID: 26218762

SO-VID: aecfa703-2e36-49a2-b9e7-2bc87d46d30d

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