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      Reducing the number of sutures for vesicourethral anastomosis in radical retropubic prostatectomy

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          Abstract

          OBJECTIVE: To prospectively evaluate the outcome of using a two-suture technique for the vesicourethral anastomosis (VUA) during radical retropubic prostatectomy (RRP). MATERIAL AND METHODS: Two groups of 50 patients each underwent nerve-sparing RRP for localized prostate cancer by one surgeon. In one group, the vesicourethral anastomosis was performed using 2 Vicryl 2-0 stitches placed at the 3- and 9-o’clock positions and in the other group 6 Vicryl 2-0 stitches were placed at the 2-, 4-, 6-, 8-, 10- and 12-o’clock positions. The intraoperative and perioperative parameters analyzed were time to perform the VUA, time to remove the drain and hospitalization. The rate of incontinence, anastomotic stricture and erectile function were included in the outcome analysis. RESULTS: The anastomotic time differed statistically between the 2 groups (mean 3.3 minutes for the 2-suture group and 10.5 minutes for the 6-suture group, p < 0.0001) with similar periods of drain removal (mean 3.12 days for the 2-suture group and 3.45 days for the 6-suture group; p = 0.13) and hospitalization (mean 4.66 days for the 2-suture group and 5.3 days for the 6-suture group; p = 0.09). The functional outcome was excellent for the 2-suture group with no patient suffering from incontinence or anastomotic strictures 1 year postoperatively, while in the 6-suture group there were 2 patients (4%) suffering from incontinence (2 underwent sling procedure) and 1 patient suffered from anastomotic stricture. CONCLUSION: The low number of sutures in the 2-suture VUA technique reduces operating times, does not influence perioperative and intraoperative parameters and results in excellent functional outcome.

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          Most cited references20

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          Anatomic radical prostatectomy: evolution of the surgical technique.

          P C Walsh (1998)
          Although radical prostatectomy provided excellent cancer control, it never gained widespread popularity because of the major side effects of incontinence, impotence and excessive blood loss. The reason for this morbidity was a deficit in the understanding of the periprostatic anatomy. The evolution of the surgical technique for anatomic radical prostatectomy is described. Beginning in 1974 anatomic observations in the operating room were used to clarify the anatomy of the dorsal vein complex, pelvic plexus, striated urethral sphincter and lateral pelvic fascia. These intraoperative observations were amplified using dissections in stillborns and step section whole mount adult cadaveric studies. Armed with improved information about the periprostatic anatomy, an anatomical approach to radical prostatectomy was developed. This surgical technique has improved surgical exposure, lowered blood loss, reduced urinary incontinence, made it possible to preserve potency and provided excellent cancer control. With the reduction in morbidity, radical prostatectomy today is an ideal treatment for the cure of prostate cancer in a patient who is curable and who is going to live long enough to need to be cured. Also the widespread application of radical prostatectomy has provided tissue and valuable pathological information that has galvanized research in the field.
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            Risk factors for urinary incontinence after radical prostatectomy.

            We identified risk factors associated with urinary incontinence after radical retropubic prostatectomy. The time from operation until urinary continence was achieved was determined by chart review and questionnaire in 581 patients who were continent before undergoing radical retropubic prostatectomy between 1983 and 1994. Using univariate and multivariate analyses of data gathered prospectively, we examined risk factors associated with incontinence in these patients. The actuarial rate of urinary continence at 24 months was 91% for the entire patient population and 95% for those treated after 1990. Many factors were associated with the risk of incontinence in univariate Cox proportional hazards regression analysis (patient age and weight, degree of obstructive voiding symptoms, prior transurethral resection of the prostate, clinical stage, intraoperative blood loss, resection of neurovascular bundles, postoperative anastomotic stricture and technique of vesicourethral anastomosis). However, in a multivariate analysis the factors that were independently associated with increased chance of regaining continence were decreasing age, a modification in the technique of anastomosis (introduced in 1990), preservation of both neurovascular bundles and absence of an anastomotic stricture. With introduction of the new surgical technique in 1990 the median time to continence decreased from 5.6 to 1.5 months and the rate of continence at 24 months increased from 82 to 95%. While the risk of urinary incontinence after radical prostatectomy is related to the uncontrollable factor of patient age, it is also sensitive to the surgical technique used.
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              Effect of pelvic-floor re-education on duration and degree of incontinence after radical prostatectomy: a randomised controlled trial.

              Urinary incontinence is a common long-term complication after radical prostatectomy. Spontaneous recovery of normal urinary control after surgery can take 1-2 years. We aimed to investigate whether there was any beneficial effect of pelvic-floor re-education for patients with urinary incontinence as a result of radical prostatectomy. 102 consecutive incontinent patients who had had radical retropubic prostatectomy for clinically localised prostate cancer and who could comply with the ambulatory treatment schedule in our hospital were randomised, after catheter removal, into a treatment group (n=50) and a control group (n=52). Patients in the treatment group took part in a pelvic-floor re-education programme for as long as they were incontinent, and for a maximum of 1 year. The control group received placebo therapy. The primary endpoint was continence rate at 3 months. Incontinence was assessed objectively with the 1 h and 24 h pad tests and subjectively by the visual analogue scale. The groups were analysed on an intention-to-treat basis by ANOVA and chi2-test. In the treatment group continence was achieved after 3 months in 43 (88%) of 48 patients. In the control group, continence returned after 3 months in 29 (56%) of 52 patients. At 1 year, the difference in proportion between treatment and control group was 14% (95% CI 2-27). In the treatment group improvement in both duration (log-rank test, p=0.0001) and degree of incontinence (Wald test, p=0.0010) was significantly better than in the control group. Pelvic-floor re-education should be considered as a first-line option in curing incontinence after radical prostatectomy.
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                Author and article information

                Journal
                ibju
                International braz j urol
                Int. braz j urol.
                Sociedade Brasileira de Urologia (Rio de Janeiro, RJ, Brazil )
                1677-5538
                1677-6119
                April 2009
                : 35
                : 2
                : 158-163
                Affiliations
                [01] Athens orgnameUniversity of Athens orgdiv1Sismanoglio Hospital orgdiv2Second Department of Urology Greece
                Article
                S1677-55382009000200005 S1677-5538(09)03500205
                10.1590/S1677-55382009000200005
                add305e1-be25-470e-88f1-788701e4ae9c

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 14 November 2008
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 20, Pages: 6
                Product

                SciELO Brazil

                Categories
                Clinical Urology

                prostatectomy,treatment outcome,prostatic neoplasm,sutures,surgical,anastomosis

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