DCE-MRI of the prostate using shutter-speed vs. Tofts model for tumor characterization and assessment of aggressiveness.

Hectors, Stefanie J. C. G.; Besa, Cecilia; Wagner, Mathilde; Jajamovich, Guido H.; Haines, George K.; Lewis, Sara; Tewari, Ashutosh; Rastinehad, Ardeshir R.; Huang, Wei; Taouli, Bachir

doi:10.1002/jmri.25631

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DCE-MRI of the prostate using shutter-speed vs. Tofts model for tumor characterization and assessment of aggressiveness.

Author(s): Stefanie J Hectors, Cecilia Besa, Mathilde Wagner, Guido H Jajamovich, George K Haines, Sara Lewis, Ashutosh Tewari, Ardeshir Rastinehad, Wei Huang, Bachir Taouli

Publication date: 2017-09-01

Journal: Journal of magnetic resonance imaging : JMRI

Publisher: Wiley

Keywords: prostate cancer, shutter-speed, Tofts, DCE-MRI

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Abstract

To quantify Tofts model (TM) and shutter-speed model (SSM) perfusion parameters in prostate cancer (PCa) and noncancerous peripheral zone (PZ) and to compare the diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to Prostate Imaging and Reporting and Data System (PI-RADS) classification for the assessment of PCa aggressiveness.