Regulatory RNAs in bacteria.

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Abstract

Bacteria possess numerous and diverse means of gene regulation using RNA molecules, including mRNA leaders that affect expression in cis, small RNAs that bind to proteins or base pair with target RNAs, and CRISPR RNAs that inhibit the uptake of foreign DNA. Although examples of RNA regulators have been known for decades in bacteria, we are only now coming to a full appreciation of their importance and prevalence. Here, we review the known mechanisms and roles of regulatory RNAs, highlight emerging themes, and discuss remaining questions.

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Journal

Journal ID (iso-abbrev): Cell

Title: Cell

Publisher: Elsevier BV

ISSN (Electronic): 1097-4172

ISSN (Print): 0092-8674

Publication date (Electronic): Feb 20 2009

Volume: 136

Issue: 4

Affiliations

[1 ] Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892, USA.

Article

Publisher Item ID: S0092-8674(09)00125-1 Mid ID: NIHMS302082

DOI: 10.1016/j.cell.2009.01.043

PMC ID: 3132550

PubMed ID: 19239884

SO-VID: ad36d21b-9d37-45e4-af3e-d677d1c33189

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