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Cefiderocol versus high-dose, extended-infusion meropenem for the treatment of Gram-negative nosocomial pneumonia (APEKS-NP): a randomised, double-blind, phase 3, non-inferiority trial
Richard G Wunderink ,
Yuko Matsunaga ,
Mari Ariyasu ,
Philippe Clevenbergh ,
Roger Echols ,
Keith S Kaye ,
Marin Kollef ,
Anju Menon ,
Jason M Pogue ,
Andrew F Shorr ,
Jean-Francois Timsit ,
Markus Zeitlinger ,
Tsutae D Nagata
October 2020
October 2020
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Abstract
<p class="first" id="d4711272e239">Nosocomial pneumonia due to multidrug-resistant
Gram-negative pathogens poses an increasing
challenge. We compared the efficacy and safety of cefiderocol versus high-dose, extended-infusion
meropenem for adults with nosocomial pneumonia.
</p>