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      Selective Intra-Arterial Embolization for Advanced Extrascleral Uveal Melanoma

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          Abstract

          Purpose: To report a treatment approach for advanced extrascleral uveal melanoma. Methods: We performed clinical examination including magnetic resonance imaging, computed tomography, angiography, and histopathologic analysis. Case: A 49-year-old healthy woman presented with a 7-year history of an enlarging pigmented mass in her right orbit. Malignant melanoma was diagnosed after biopsy with immunohistochemical stains. Treatment included selective intra-arterial embolization. Results: A significant reduction in tumor burden was seen 3 months after intra-arterial embolization. No complications were associated with the treatment. Conclusion: Selective intra-arterial embolization may allow adequate palliative therapy in select cases of advanced extrascleral uveal melanoma.

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          Author and article information

          Journal
          OOP
          OOP
          10.1159/issn.2296-4657
          Ocular Oncology and Pathology
          S. Karger AG
          2296-4681
          2296-4657
          2018
          December 2017
          19 July 2017
          : 4
          : 1
          : 44-47
          Affiliations
          aDepartment of Ophthalmology, University of Puerto Rico, Río Piedras, Puerto Rico; bBascom Palmer Eye Institute, University of Miami, and cMurray Ocular Oncology and Retina, Miami, FL, USA
          Author notes
          *Víctor M. Villegas, MD, Bascom Palmer Eye Institute, 900 NW 17th Street, Miami, FL 33136 (USA), E-Mail v.villegas@med.miami.edu
          Article
          477772 PMC5757620 Ocul Oncol Pathol 2018;4:44-47
          10.1159/000477772
          PMC5757620
          29344498
          abfdf8cb-b24a-426d-a788-0a91f7d336c8
          © 2017 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 21 April 2017
          : 22 May 2017
          Page count
          Figures: 5, References: 13, Pages: 4
          Categories
          Original Paper

          Vision sciences,Ophthalmology & Optometry,Pathology
          Melanoma,Ocular melanoma,Malignant melanoma
          Vision sciences, Ophthalmology & Optometry, Pathology
          Melanoma, Ocular melanoma, Malignant melanoma

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