Evaluation of genotype MTBDRplus line probe assay in detection of rifampicin and isoniazid resistance in comparison to solid culture drug susceptibility testing in a tertiary care centre of western Uttar Pradesh.

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Abstract

Isoniazid (INH) and rifampicin (Rif) are the key first-line antituberculosis drugs, and resistance to these drugs i.e., multi-drug-resistant tuberculosis (MDR-TB), is likely to result in treatment failure and poor clinical outcomes. India has the highest burden of TB and MDR-TB in the world, disproportionately high even for India's population. The GenoType® MTBDRplus molecular method allows rapid detection of Rif and INH resistance.

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Journal

Journal ID (iso-abbrev): Indian J Med Microbiol

Title: Indian journal of medical microbiology

Publisher: Medknow

ISSN (Electronic): 1998-3646

ISSN (Print): 0255-0857

Publication date (Electronic): February 7 2018

Volume: 35

Issue: 4

Affiliations

[1 ] Department of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

[2 ] Department of TB and Respiratory Diseases, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

Article

Publisher Item ID: IndianJMedMicrobiol_2017_35_4_568_224435

DOI: 10.4103/ijmm.IJMM_17_321

PubMed ID: 29405151

SO-VID: aa983e69-310b-4dab-a97c-2682202a8348

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