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Association of 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D and parathyroid hormone with mortality among middle-aged and older European men
D. M. Lee ,
D. Vanderschueren ,
S. Boonen ,
T. W. O'Neill ,
N. Pendleton ,
S. R. Pye ,
R. Ravindrarajah ,
E. Gielen ,
F. Claessens ,
G. Bartfai ,
F. F. Casanueva ,
J. D. Finn ,
G. Forti ,
A. Giwercman ,
T. S. Han ,
I. T. Huhtaniemi ,
K. Kula ,
M. E. J. Lean ,
M. Punab ,
F. C. W. Wu
1
June 23 2014
December 26 2013
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Abstract
vitamin D deficiency has been associated with an increased risk of mortality, but
whether this relationship is causal or linked to co-existent comorbidity and adverse
life factors remains uncertain. Our objective was to determine whether endogenous
25-hydroxyvitamin D (25(OH)D), 1,25-dihydroxyvitamin D (1,25(OH)2D) and parathyroid
hormone (PTH) levels predicted all-cause, cardiovascular and cancer mortality independently
of health and lifestyle factors.
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