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      An integrative machine learning framework for classifying SEER breast cancer

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      1 , , 1 , 2 ,
      Scientific Reports
      Nature Publishing Group UK
      Breast cancer, Machine learning

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          Abstract

          Breast cancer is the commonest type of cancer in women worldwide and the leading cause of mortality for females. The aim of this research is to classify the alive and death status of breast cancer patients using the Surveillance, Epidemiology, and End Results dataset. Due to its capacity to handle enormous data sets systematically, machine learning and deep learning has been widely employed in biomedical research to answer diverse classification difficulties. Pre-processing the data enables its visualization and analysis for use in making important decisions. This research presents a feasible machine learning-based approach for categorizing SEER breast cancer dataset. Moreover, a two-step feature selection method based on Variance Threshold and Principal Component Analysis was employed to select the features from the SEER breast cancer dataset. After selecting the features, the classification of the breast cancer dataset is carried out using Supervised and Ensemble learning techniques such as Ada Boosting, XG Boosting, Gradient Boosting, Naive Bayes and Decision Tree. Utilizing the train-test split and k-fold cross-validation approaches, the performance of various machine learning algorithms is examined. The accuracy of Decision Tree for both train-test split and cross validation achieved as 98%. In this study, it is observed that the Decision Tree algorithm outperforms other supervised and ensemble learning approaches for the SEER Breast Cancer dataset.

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          Current and future burden of breast cancer: Global statistics for 2020 and 2040

          Background Breast cancer is the most commonly diagnosed cancer worldwide, and its burden has been rising over the past decades. In this article, we examine and describe the global burden of breast cancer in 2020 and predictions for the year 2040. Methods Estimates of new female breast cancer cases and deaths in 2020 were abstracted from the GLOBOCAN database. Age-standardized incidence and mortality rates were calculated per 100,000 females by country, world region, and level of human development. Predicted cases and deaths were computed based on global demographic projections for the year 2040. Results Over 2.3 million new cases and 685,000 deaths from breast cancer occurred in 2020. Large geographic variation across countries and world regions exists, with incidence rates ranging from <40 per 100,000 females in some Asian and African countries, to over 80 per 100,000 in Australia/New Zealand, Northern America, and parts of Europe. Smaller geographical variation was observed for mortality; however, transitioning countries continue to carry a disproportionate share of breast cancer deaths relative to transitioned countries. By 2040, the burden from breast cancer is predicted to increase to over 3 million new cases and 1 million deaths every year because of population growth and ageing alone. Conclusion Breast cancer is the most common cancer worldwide and continues to have a large impact on the global number of cancer deaths. Global efforts are needed to counteract its growing burden, especially in transitioning countries where incidence is rising rapidly, and mortality rates remain high. • With over 2.3 million new cases and 685,000 deaths in 2020, breast cancer is the most commonly diagnosed cancer worldwide. • Most cases occur in transitioned countries yet transitioning countries have disproportionate share of breast cancer deaths. • The future burden of breast cancer is predicted to increase to over 3 million new cases and 1 million deaths in 2040.
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            Artificial intelligence in cancer imaging: Clinical challenges and applications

            Abstract Judgement, as one of the core tenets of medicine, relies upon the integration of multilayered data with nuanced decision making. Cancer offers a unique context for medical decisions given not only its variegated forms with evolution of disease but also the need to take into account the individual condition of patients, their ability to receive treatment, and their responses to treatment. Challenges remain in the accurate detection, characterization, and monitoring of cancers despite improved technologies. Radiographic assessment of disease most commonly relies upon visual evaluations, the interpretations of which may be augmented by advanced computational analyses. In particular, artificial intelligence (AI) promises to make great strides in the qualitative interpretation of cancer imaging by expert clinicians, including volumetric delineation of tumors over time, extrapolation of the tumor genotype and biological course from its radiographic phenotype, prediction of clinical outcome, and assessment of the impact of disease and treatment on adjacent organs. AI may automate processes in the initial interpretation of images and shift the clinical workflow of radiographic detection, management decisions on whether or not to administer an intervention, and subsequent observation to a yet to be envisioned paradigm. Here, the authors review the current state of AI as applied to medical imaging of cancer and describe advances in 4 tumor types (lung, brain, breast, and prostate) to illustrate how common clinical problems are being addressed. Although most studies evaluating AI applications in oncology to date have not been vigorously validated for reproducibility and generalizability, the results do highlight increasingly concerted efforts in pushing AI technology to clinical use and to impact future directions in cancer care.
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              Automated diagnosis of breast ultrasonography images using deep neural networks

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                Author and article information

                Contributors
                manimkn89@gmail.com
                cponnuraja@gmail.com
                Journal
                Sci Rep
                Sci Rep
                Scientific Reports
                Nature Publishing Group UK (London )
                2045-2322
                1 April 2023
                1 April 2023
                2023
                : 13
                : 5362
                Affiliations
                [1 ]GRID grid.413015.2, ISNI 0000 0004 0505 215X, Department of Data Science, , Loyola College, ; Chennai, 600 034 India
                [2 ]GRID grid.417330.2, ISNI 0000 0004 1767 6138, ICMR-National Institute for Research in Tuberculosis, ; Chennai, 600 031 India
                Article
                32029
                10.1038/s41598-023-32029-1
                10067827
                a8c8ee95-ba51-4e9f-a246-8cc83c0d5250
                © The Author(s) 2023

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 23 January 2023
                : 21 March 2023
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                © The Author(s) 2023

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                breast cancer,machine learning
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