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      Fatores de virulência de Candida spp isoladas de cateteres venosos e mãos de servidores hospitalares Translated title: Virulence factors for Candida spp recovered from intravascular catheters and hospital workers’ hands

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          Abstract

          Avaliou-se o potencial de virulência de 23 leveduras isoladas de cateteres e mãos de trabalhadores em um hospital do Noroeste do Paraná. As leveduras isoladas de cateter foram mais aderentes e hidrofóbicas (P<0,05) que as leveduras isoladas das mãos. Candida não-albicans expressaram com mais intensidade os fatores de virulência avaliados.

          Translated abstract

          The virulence potential of 23 yeasts recovered from intravascular catheters and the hands of workers in a hospital in the northwestern region of Paraná were evaluated. Yeasts recovered from catheters presented greater adherence and were more hydrophobic (p<0.05) than yeasts recovered from hands. Candida non-albicans species expressed the virulence factors evaluated more intensely.

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          Contamination, Disinfection, and Cross-Colonization: Are Hospital Surfaces Reservoirs for Nosocomial Infection?

          Robert Weinstein, Bala Hota (2004)
          Abstract Despite documentation that the inanimate hospital environment (e.g., surfaces and medical equipment) becomes contaminated with nosocomial pathogens, the data that suggest that contaminated fomites lead to nosocomial infections do so indirectly. Pathogens for which there is more-compelling evidence of survival in environmental reservoirs include Clostridium difficile, vancomycin-resistant enterococci, and methicillin-resistant Staphylococcus aureus, and pathogens for which there is evidence of probable survival in environmental reservoirs include norovirus, influenza virus, severe acute respiratory syndrome—associated coronavirus, and Candida species. Strategies to reduce the rates of nosocomial infection with these pathogens should conform to established guidelines, with an emphasis on thorough environmental cleaning and use of Environmental Protection Agency—approved detergent-disinfectants.
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            Susceptibility profile of 200 bloodstream isolates of Candida spp. collected from Brazilian tertiary care hospitals.

            A Colombo, Z Nakagawa, F Valdetaro … (2003)
            We evaluated the antifungal susceptibility profile of 200 recent bloodstream isolates of Candida spp. sequentially obtained from patients admitted to five tertiary care hospitals in Brazil. Isolates were identified by classical methods and the antifungal susceptibility profile was determined by the NCCLS microbroth assay method. Candida albicans was the most frequent species (41.5%); followed by C. tropicalis (24%) and C. parapsilosis (20.5%). The frequency of C. glabrata and C. krusei was low (nine and two isolates, respectively). Only three strains were resistant to fluconazole (two C. krusei and one C. glabrata) and only one was resistant to itraconazole (the same C. glabrata strain that was resistant to fluconazole). Two strains were considered susceptible dose-dependent (SDD) to fluconazole and 13 isolates (6.5%) were SDD to itraconazole. Overall, the MIC50 value of non-C. albicans isolates for fluconazole was two dilutions higher than that of C. albicans isolates, and for itraconazole was one dilution higher. Resistance to amphotericin B (MIC > or = 2 microg ml(-1)) was observed in 2.5% of isolates (two strains of C. albicans, two of C. parapsilosis and one of C. krusei). This study showed that episodes of candidemia in Brazilian public hospitals are represented mainly by fluconazole-susceptible non-C. albicans species. This finding is probably related to the low use of fluconazole in these hospitals.
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              The yeasts: a taxonomic study

              CP KURTZMAN, JW Fell, CP Kurtzman (1998)
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                Author and article information

                Contributors
                Nathalie Kira Tamura: Role: ND
                Melyssa Fernanda Norman Negri: Role: ND
                Lucineide Aparecida Bonassoli: Role: ND
                Terezinha Inez Estivalet Svidzinski: Role: ND
                Journal
                Journal ID (publisher): rsbmt
                Title: Revista da Sociedade Brasileira de Medicina Tropical
                Abbreviated Title: Rev. Soc. Bras. Med. Trop.
                Publisher: Sociedade Brasileira de Medicina Tropical - SBMT (Uberaba )
                ISSN: 1678-9849
                Publication date (Print): February 2007
                Volume: 40
                Issue: 1
                Pages: 91-93
                Affiliations
                [1 ] Hospital Universitário de Maringá
                [2 ] Universidade de São Paulo
                [3 ] Universidade Estadual de Maringá Brazil
                Article
                Publisher ID: S0037-86822007000100021
                DOI: 10.1590/S0037-86822007000100021
                SO-VID: a89c2e5b-ae07-4ff5-8ba3-4d73592dfab3
                License:

                http://creativecommons.org/licenses/by/4.0/

                History
                Product

                SciELO Brazil

                Self URI (journal page): http://www.scielo.br/scielo.php?script=sci_serial&pid=0037-8682&lng=en
                Categories
                Subject: TROPICAL MEDICINE

                ScienceOpen disciplines: Infectious disease & Microbiology
                Keywords: Candida sp,Hospital devices,Hands,Nosocomial infection risks,Dispositivos hospitalares,Mãos,Riscos de infecção hospitalar
                Data availability:
                ScienceOpen disciplines: Infectious disease & Microbiology
                Keywords: Candida sp, Hospital devices, Hands, Nosocomial infection risks, Dispositivos hospitalares, Mãos, Riscos de infecção hospitalar

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