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      Emerging dynamic memristors for neuromorphic reservoir computing

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          Abstract

          This work reviews the state-of-the-art physical reservoir computing systems based on dynamic memristors integrating with unique nonlinear dynamics and short-term memory behavior. The key characteristics, challenges and perspectives are also discussed.

          Abstract

          Reservoir computing (RC), as a brain-inspired neuromorphic computing algorithm, is capable of fast and energy-efficient temporal data analysis and prediction. Hardware implementation of RC systems can significantly reduce the computing time and energy, but it is hindered by current physical devices. Recently, dynamic memristors have proved to be promising for hardware implementation of such systems, benefiting from their fast and low-energy switching, nonlinear dynamics, and short-term memory behavior. In this work, we review striking results that leverage dynamic memristors to enhance the data processing abilities of RC systems based on resistive switching devices and magnetoresistive devices. The critical characteristic parameters of memristors affecting the performance of RC systems, such as reservoir size and decay time, are identified and discussed. Finally, we summarize the challenges this field faces in reliable and accurate task processing, and forecast the future directions of RC systems.

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          Most cited references63

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          Structural absorption by barbule microstructures of super black bird of paradise feathers

          Many studies have shown how pigments and internal nanostructures generate color in nature. External surface structures can also influence appearance, such as by causing multiple scattering of light (structural absorption) to produce a velvety, super black appearance. Here we show that feathers from five species of birds of paradise (Aves: Paradisaeidae) structurally absorb incident light to produce extremely low-reflectance, super black plumages. Directional reflectance of these feathers (0.05–0.31%) approaches that of man-made ultra-absorbent materials. SEM, nano-CT, and ray-tracing simulations show that super black feathers have titled arrays of highly modified barbules, which cause more multiple scattering, resulting in more structural absorption, than normal black feathers. Super black feathers have an extreme directional reflectance bias and appear darkest when viewed from the distal direction. We hypothesize that structurally absorbing, super black plumage evolved through sensory bias to enhance the perceived brilliance of adjacent color patches during courtship display.
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            In situ click chemistry generation of cyclooxygenase-2 inhibitors

            Cyclooxygenase-2 isozyme is a promising anti-inflammatory drug target, and overexpression of this enzyme is also associated with several cancers and neurodegenerative diseases. The amino-acid sequence and structural similarity between inducible cyclooxygenase-2 and housekeeping cyclooxygenase-1 isoforms present a significant challenge to design selective cyclooxygenase-2 inhibitors. Herein, we describe the use of the cyclooxygenase-2 active site as a reaction vessel for the in situ generation of its own highly specific inhibitors. Multi-component competitive-binding studies confirmed that the cyclooxygenase-2 isozyme can judiciously select most appropriate chemical building blocks from a pool of chemicals to build its own highly potent inhibitor. Herein, with the use of kinetic target-guided synthesis, also termed as in situ click chemistry, we describe the discovery of two highly potent and selective cyclooxygenase-2 isozyme inhibitors. The in vivo anti-inflammatory activity of these two novel small molecules is significantly higher than that of widely used selective cyclooxygenase-2 inhibitors.
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              Nanoscale memristor device as synapse in neuromorphic systems.

              A memristor is a two-terminal electronic device whose conductance can be precisely modulated by charge or flux through it. Here we experimentally demonstrate a nanoscale silicon-based memristor device and show that a hybrid system composed of complementary metal-oxide semiconductor neurons and memristor synapses can support important synaptic functions such as spike timing dependent plasticity. Using memristors as synapses in neuromorphic circuits can potentially offer both high connectivity and high density required for efficient computing.
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                Author and article information

                Contributors
                Journal
                NANOHL
                Nanoscale
                Nanoscale
                Royal Society of Chemistry (RSC)
                2040-3364
                2040-3372
                January 06 2022
                2022
                : 14
                : 2
                : 289-298
                Affiliations
                [1 ]Frontier Institute of Chip and System, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai 200433, China
                [2 ]State Key Laboratory of ASIC and System, School of Microelectronics, Fudan University, Shanghai 200433, China
                [3 ]Shanghai Qi Zhi Institute, 41th Floor, AI Tower, No. 701 Yunjin Road, Xuhui District, Shanghai 200232, China
                [4 ]Institute of Materials Research and Engineering (A*STAR), 2 Fusionopolis Way, 138634, Singapore
                Article
                10.1039/D1NR06680C
                34932057
                a890d090-fe84-41de-9e94-28bfdfebd1c2
                © 2022

                http://rsc.li/journals-terms-of-use

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