Risk of neurosyphilis in HIV-infected persons with syphilis lacking signs or symptoms of central nervous system infection.

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Abstract

People living with HIV (PLWH) are at increased risk of asymptomatic neurosyphilis; thus, it has been common practice to perform a lumbar puncture (LP) in all PLWH presenting with syphilis regardless of stage, signs or symptoms. However, this practice varies widely among clinicians. Our objective was to elucidate the number of LPs required to diagnose a single case of asymptomatic neurosyphilis.

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Journal

Journal ID (iso-abbrev): HIV Med.

Title: HIV medicine

Publisher: Wiley

ISSN (Electronic): 1468-1293

ISSN (Print): 1464-2662

Publication date (Electronic): January 2019

Volume: 20

Issue: 1

Affiliations

[1 ] Department of Internal Medicine, University of Illinois at Chicago, Chicago, IL, USA.

[2 ] Division of Infectious Diseases, Immunology & International Medicine, University of Illinois at Chicago, Chicago, IL, USA.

[3 ] School of Public Health, University of Illinois at Chicago, Chicago, IL, USA.

[4 ] Jesse Brown Veterans Affairs Medical Center, Chicago, IL, USA.

Article

DOI: 10.1111/hiv.12677

PubMed ID: 30402918

SO-VID: a88b75d5-84c5-4548-a036-6937774bcd15

History

Keywords: syphilis,neurosyphilis,lumbar puncture, HIV

Data availability:

Keywords: syphilis, neurosyphilis, lumbar puncture, HIV

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