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      [Evaluation of the efficacy of wiferon and arbidol in adult influenza].

      Voprosy virusologii
      Administration, Rectal, Adolescent, Adult, Antiviral Agents, administration & dosage, therapeutic use, Cough, drug therapy, Double-Blind Method, Fever, Humans, Indoles, Influenza, Human, blood, immunology, Interferon-alpha, Interferons, biosynthesis, Leukocytes, metabolism, Lymphocyte Count, Middle Aged, Recombinant Proteins, Rhinitis, Suppositories, Treatment Outcome

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          Abstract

          The therapeutic efficacy of wiferon (recombinant alpha2beta-interferon) versus arbidol was studied in a double-blind controlled study in patients with laboratorily verified influenza. Within the first 24-36 hours after the onset of the disease, wiferon and arbidol reduced the duration of fever, intoxication, and the catarrhal symptoms of the disease as a whole. The agents were shown to have an immunomodulating effect.

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