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      Computerized Clinical Decision Support System for Emergency Department–Initiated Buprenorphine for Opioid Use Disorder: User-Centered Design

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          Abstract

          Background

          Emergency departments (EDs) frequently care for individuals with opioid use disorder (OUD). Buprenorphine (BUP) is an effective treatment option for patients with OUD that can safely be initiated in the ED. At present, BUP is rarely initiated as a part of routine ED care. Clinical decision support (CDS) could accelerate adoption of ED-initiated BUP into routine emergency care.

          Objective

          This study aimed to design and formatively evaluate a user-centered decision support tool for ED initiation of BUP for patients with OUD.

          Methods

          User-centered design with iterative prototype development was used. Initial observations and interviews identified workflows and information needs. The design team and key stakeholders reviewed prototype designs to ensure accuracy. A total of 5 prototypes were evaluated and iteratively refined based on input from 26 attending and resident physicians.

          Results

          Early feedback identified concerns with the initial CDS design: an alert with several screens. The timing of the alert led to quick dismissal without using the tool. User feedback on subsequent iterations informed the development of a flexible tool to support clinicians with varied levels of experience with the intervention by providing both one-click options for direct activation of care pathways and user-activated support for critical decision points. The final design resolved challenging navigation issues through targeted placement, color, and design of the decision support modules and care pathways. In final testing, users expressed that the tool could be easily learned without training and was reasonable for use during routine emergency care.

          Conclusions

          A user-centered design process helped designers to better understand users’ needs for a Web-based clinical decision tool to support ED initiation of BUP for OUD. The process identified varying needs across user experience and familiarity with the protocol, leading to a flexible design supporting both direct care pathways and user-initiated decision support.

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          Most cited references26

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          Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review.

          Developers of health care software have attributed improvements in patient care to these applications. As with any health care intervention, such claims require confirmation in clinical trials. To review controlled trials assessing the effects of computerized clinical decision support systems (CDSSs) and to identify study characteristics predicting benefit. We updated our earlier reviews by searching the MEDLINE, EMBASE, Cochrane Library, Inspec, and ISI databases and consulting reference lists through September 2004. Authors of 64 primary studies confirmed data or provided additional information. We included randomized and nonrandomized controlled trials that evaluated the effect of a CDSS compared with care provided without a CDSS on practitioner performance or patient outcomes. Teams of 2 reviewers independently abstracted data on methods, setting, CDSS and patient characteristics, and outcomes. One hundred studies met our inclusion criteria. The number and methodologic quality of studies improved over time. The CDSS improved practitioner performance in 62 (64%) of the 97 studies assessing this outcome, including 4 (40%) of 10 diagnostic systems, 16 (76%) of 21 reminder systems, 23 (62%) of 37 disease management systems, and 19 (66%) of 29 drug-dosing or prescribing systems. Fifty-two trials assessed 1 or more patient outcomes, of which 7 trials (13%) reported improvements. Improved practitioner performance was associated with CDSSs that automatically prompted users compared with requiring users to activate the system (success in 73% of trials vs 47%; P = .02) and studies in which the authors also developed the CDSS software compared with studies in which the authors were not the developers (74% success vs 28%; respectively, P = .001). Many CDSSs improve practitioner performance. To date, the effects on patient outcomes remain understudied and, when studied, inconsistent.
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            Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence

            Cochrane Database of Systematic Reviews
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              • Record: found
              • Abstract: found
              • Article: not found

              Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial.

              Opioid-dependent patients often use the emergency department (ED) for medical care.
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                Author and article information

                Contributors
                Journal
                JMIR Hum Factors
                JMIR Hum Factors
                JMIR Human Factors
                JMIR Human Factors
                JMIR Publications (Toronto, Canada )
                2292-9495
                Jan-Mar 2019
                27 February 2019
                : 6
                : 1
                : e13121
                Affiliations
                [1 ] Yale School of Medicine New Haven, CT United States
                [2 ] Yale New Haven Health New Haven, CT United States
                [3 ] The Patient Revolution New Haven, CT United States
                [4 ] Mayo Clinic Rochester, MN United States
                [5 ] University of North Carolina School of Medicine Chapel Hill, NC United States
                [6 ] University of Alabama at Birmingham School of Medicine Birmingham, AL United States
                Author notes
                Corresponding Author: Edward R Melnick edward.melnick@ 123456yale.edu
                Author information
                http://orcid.org/0000-0003-3410-1507
                http://orcid.org/0000-0003-1492-9868
                http://orcid.org/0000-0002-8963-5664
                http://orcid.org/0000-0003-2704-4575
                http://orcid.org/0000-0001-5904-9122
                http://orcid.org/0000-0003-3854-6810
                http://orcid.org/0000-0002-9881-3194
                http://orcid.org/0000-0002-6499-9592
                http://orcid.org/0000-0002-3833-1871
                http://orcid.org/0000-0002-6509-9537
                Article
                v6i1e13121
                10.2196/13121
                6414819
                30810531
                a749322c-a198-4e8a-81df-1482ab1a16a3
                ©Jessica M Ray, Osama M Ahmed, Yauheni Solad, Matthew Maleska, Shara Martel, Molly M Jeffery, Timothy F Platts-Mills, Erik P Hess, Gail D’Onofrio, Edward R Melnick. Originally published in JMIR Human Factors (http://humanfactors.jmir.org), 27.02.2019.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Human Factors, is properly cited. The complete bibliographic information, a link to the original publication on http://humanfactors.jmir.org.as well as this copyright and license information must be included.

                History
                : 15 December 2018
                : 10 January 2019
                : 1 February 2019
                : 9 February 2019
                Categories
                Original Paper
                Original Paper

                user-centered design,decision support systems, clinical,opioid-related disorders,opiate substitution treatment,health information technology

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