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      Occupational therapy for people with dementia and their family carers provided at home: a systematic review and meta-analysis

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          Abstract

          Objective

          To determine the effect of occupational therapy provided at home on activities of daily living, behavioural and psychological symptoms of dementia (BPSD) and quality of life (QOL) for people with dementia, and the effect on family carer burden, depression and QOL.

          Design

          Systematic review and meta-analysis.

          Methods

          Eight databases were searched to February 2018. Randomised controlled trials of occupational therapy delivered at home for people with dementia and their family carers that measured ADL, and/or BPSD were included. Two independent reviewers determined eligibility, risk of bias and extracted data.

          Results

          Fifteen trials were included (n=2063). Occupational therapy comprised multiple components (median=8 sessions). Compared with usual care or attention control occupational therapy resulted in improvements in the following outcomes for people with dementia: overall ADL after intervention (standardised means difference (SMD) 0.61, 95% CI 0.16 to 1.05); instrumental ADL alone (SMD 0.22, 95% CI 0.07 to 0.37; moderate quality); number of behavioural and psychological symptoms (SMD −0.32, 95% CI −0.57 to −0.08; moderate quality); and QOL (SMD 0.76, 95% CI 0.28 to 1.24) after the intervention and at follow-up (SMD 1.07, 95% CI 0.58 to 1.55). Carers reported less hours assisting the person with dementia (SMD −0.33, 95% CI −0.58 to −0.07); had less distress with behaviours (SMD −0.23, 95% CI −0.42 to −0.05; moderate quality) and improved QOL (SMD 0.99, 95% CI 0.66 to 1.33; moderate quality). Two studies compared occupational therapy with a comparison intervention and found no statistically significant results. GRADE ratings indicated evidence was very low to moderate quality.

          Conclusions

          Findings suggest that occupational therapy provided at home may improve a range of important outcomes for people with dementia and their family carers. Health professionals could consider referring them for occupational therapy.

          PROSPERO registration number

          CRD42011001166.

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          Most cited references31

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          Family caregivers of people with dementia

          Family caregivers of people with dementia, often called the invisible second patients, are critical to the quality of life of the care recipients. The effects of being a family caregiver, though sometimes positive, are generally negative, with high rates of burden and psychological morbidity as well as social isolation, physical ill-health, and financial hardship. Caregivers vulnerable to adverse effects can be identified, as can factors which ameliorate or exacerbate burden and strain. Psychosocial interventions have been demonstrated to reduce caregiver burden and depression and delay nursing home admission. Comprehensive management of the patient with dementia includes building a partnership between health professionals and family caregivers, referral to Alzheimer's Associations, and psychosocial interventions where indicated.
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            Nonpharmacological Therapies in Alzheimer’s Disease: A Systematic Review of Efficacy

            Introduction: Nonpharmacological therapies (NPTs) can improve the quality of life (QoL) of people with Alzheimer’s disease (AD) and their carers. The objective of this study was to evaluate the best evidence on the effects of NPTs in AD and related disorders (ADRD) by performing a systematic review and meta-analysis of the entire field. Methods: Existing reviews and major electronic databases were searched for randomized controlled trials (RCTs). The deadline for study inclusion was September 15, 2008. Intervention categories and outcome domains were predefined by consensus. Two researchers working together detected 1,313 candidate studies of which 179 RCTs belonging to 26 intervention categories were selected. Cognitive deterioration had to be documented in all participants, and degenerative etiology (indicating dementia) had to be present or presumed in at least 80% of the subjects. Evidence tables, meta-analysis and summaries of results were elaborated by the first author and reviewed by author subgroups. Methods for rating level of evidence and grading practice recommendations were adapted from the Oxford Center for Evidence-Based Medicine. Results: Grade A treatment recommendation was achieved for institutionalization delay (multicomponent interventions for the caregiver, CG). Grade B recommendation was reached for the person with dementia (PWD) for: improvement in cognition (cognitive training, cognitive stimulation, multicomponent interventions for the PWD); activities of daily living (ADL) (ADL training, multicomponent interventions for the PWD); behavior (cognitive stimulation, multicomponent interventions for the PWD, behavioral interventions, professional CG training); mood (multicomponent interventions for the PWD); QoL (multicomponent interventions for PWD and CG) and restraint prevention (professional CG training); for the CG, grade B was also reached for: CG mood (CG education, CG support, multicomponent interventions for the CG); CG psychological well-being (cognitive stimulation, multicomponent interventions for the CG); CG QoL (multicomponent interventions for PWD and CG). Conclusion: NPTs emerge as a useful, versatile and potentially cost-effective approach to improve outcomes and QoL in ADRD for both the PWD and CG.
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              Alzheimer's disease

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                Author and article information

                Journal
                BMJ Open
                BMJ Open
                bmjopen
                bmjopen
                BMJ Open
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                2044-6055
                2019
                11 November 2019
                : 9
                : 11
                : e026308
                Affiliations
                [1 ] departmentSchool of Health and Rehabilitation Sciences , The University Queensland , Brisbane, Queensland, Australia
                [2 ] departmentDepartment of Rehabilitation, Aged and Extended Care , Flinders University , Adelaide, South Australia, Australia
                [3 ] departmentInstitute for Evidence in Medicine (for Cochrane Germany Foundation), Center for Geriatric Medicine and Gerontology , University of Freiburg , Germany
                [4 ] departmentSchool of Rehabilitation Science , McMaster University , Hamilton, Ontario, Canada
                [5 ] departmentFaculty of Medicine and Health , University of Sydney , Sydney, New South Wales, Australia
                [6 ] departmentIQ Healthcare & Radboud Alzheimer Centre , Radboud University , Nijmegen, The Netherlands
                [7 ] departmentCentre for Children’s Health Research , The University of Queensland , Brisbane, Queensland, Australia
                [8 ] departmentCollege of Nursing and Health Professions , Drexel University , Philadelphia, Pennsylvania, USA
                Author notes
                [Correspondence to ] Associate Professor Sally Bennett; sally.bennett@ 123456uq.edu.au
                Author information
                http://orcid.org/0000-0002-4353-5027
                Article
                bmjopen-2018-026308
                10.1136/bmjopen-2018-026308
                6858232
                31719067
                a55aa76f-b784-4a18-937a-3030c5196a74
                © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

                History
                : 26 August 2018
                : 30 July 2019
                : 31 July 2019
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100001794, University of Queensland;
                Award ID: 2007000387
                Categories
                Geriatric Medicine
                Original Research
                1506
                1698
                Custom metadata
                unlocked

                Medicine
                dementia,geriatric medicine,occupational therapy,systematic review
                Medicine
                dementia, geriatric medicine, occupational therapy, systematic review

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