GnRH antagonist versus long agonist protocols in IVF: a systematic review and meta-analysis accounting for patient type.

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Abstract

Most reviews of IVF ovarian stimulation protocols have insufficiently accounted for various patient populations, such as ovulatory women, women with polycystic ovary syndrome (PCOS) or women with poor ovarian response, and have included studies in which the agonist or antagonist was not the only variable between the compared study arms.

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Journal

Journal ID (iso-abbrev): Hum. Reprod. Update

Title: Human reproduction update

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1460-2369

ISSN (Print): 1355-4786

Publication date (Electronic): Sep 01 2017

Volume: 23

Issue: 5

Affiliations

[1 ] Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, VU University medical centre (VUmc), PO Box 7075, 1007 MB, Amsterdam, the Netherlands.

[2 ] Department of Obstetrics & Gynaecology, Fertility Clinic Section 455, Hvidovre University Hospital, Kettegård Alle 30, Hvidovre, Copenhagen 2650, Denmark.

[3 ] Homerton University Hospital NHS Foundation Trust, Homerton Row, Hackney, London E9 6SR, UK.

[4 ] Center for Reproductive Medicine, Department of Obstetrics and Gynaecology, Academic Medical Center, University of Amsterdam, PO Box 227000, 1100 DE, Amsterdam, The Netherlands.

Article

Publisher Item ID: 3965313

DOI: 10.1093/humupd/dmx017

PubMed ID: 28903472

SO-VID: a5306789-fe55-409c-a878-89964eda1fe8

History

Keywords: systematic review,GnRH agonist,meta-analysis,PCOS,poor response, polycystic ovarian syndrome,OHSS,ovarian hyperstimulation syndrome,GnRH antagonist,oral contraceptive

Data availability:

Keywords: systematic review, GnRH agonist, meta-analysis, PCOS, poor response, polycystic ovarian syndrome, OHSS, ovarian hyperstimulation syndrome, GnRH antagonist, oral contraceptive

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