Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
27
July
2017
Publication date Collection: 2017
Volume: 12
Issue: 7
Electronic Location Identifier: e0179726
Affiliations
[1
]
Translational Bioinformatics, Bristol-Myers Squibb, Redwood City, California, United
States of America
[2
]
Translational Bioinformatics, Bristol-Myers Squibb, Hopewell, New Jersey, United States
of America
[3
]
Oncology Discovery, Bristol-Myers Squibb, Lawrenceville, New Jersey, United States
of America
Universidade de Sao Paulo, BRAZIL
Author notes
Competing Interests: The authors are employed at Bristol-Myers Squibb, which discovered and commercialized
ipilimumab and nivolumab therapies for cancer. There are no patents, clinical research
programs, nor marketed products to declare that are directly related to this manuscript.
Bristol-Myers Squibb has major efforts in the area of immuno-oncology in general.
Our affiliation with Bristol-Myers Squibb does not alter our adherence to PLOS ONE
policies on sharing data and materials.
-
-
Formal analysis: NOS HC JLH SDC.
-
Investigation: NOS HC JLH PRM.
-
Methodology: NOS HC JLH SDC.
-
-
-
-
-
Writing – original draft: NOS.
-
Writing – review & editing: NOS PRM SDC JDS CFV.
Article
Publisher ID:
PONE-D-16-37475
DOI: 10.1371/journal.pone.0179726
PMC ID: 5531551
PubMed ID: 28749946
SO-VID: a36871ce-5274-42cb-82b0-acb2f4a7c36c
Copyright © © 2017 Siemers et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100002491, Bristol-Myers Squibb;
Award Recipient
:
Nathan O. Siemers
Funded by: funder-id http://dx.doi.org/10.13039/100002491, Bristol-Myers Squibb;
Award Recipient
:
James L. Holloway
Funded by: funder-id http://dx.doi.org/10.13039/100002491, Bristol-Myers Squibb;
Award Recipient
:
Han Chang
Funded by: funder-id http://dx.doi.org/10.13039/100002491, Bristol-Myers Squibb;
Award Recipient
:
Scott D. Chasalow
Funded by: funder-id http://dx.doi.org/10.13039/100002491, Bristol-Myers Squibb;
Award Recipient
:
Petra B. Ross-MacDonald
Funded by: funder-id http://dx.doi.org/10.13039/100002491, Bristol-Myers Squibb;
Award Recipient
:
Charles F. Voliva
Funded by: funder-id http://dx.doi.org/10.13039/100002491, Bristol-Myers Squibb;
Award Recipient
:
Joseph D. Szustakowski
All of the authors of this manuscript are salaried employees of Bristol-Myers Squibb
Company, a Biopharma company in the business of developing and marketing therapeutic
drugs. The Company did not influence study design, data collection, nor analysis,
but supported our research in general, and approved the release of the publication.
The specific roles of these authors are articulated in the 'author contributions'
section.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
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Immune Cells
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Biology and Life Sciences
Subject:
Immunology
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Immune Cells
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Medicine and Health Sciences
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Immunology
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Immune Cells
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Biology and Life Sciences
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Cell Biology
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Cellular Types
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Animal Cells
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Blood Cells
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White Blood Cells
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T Cells
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Biology and Life Sciences
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Cell Biology
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Cellular Types
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Animal Cells
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Immune Cells
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White Blood Cells
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T Cells
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Biology and Life Sciences
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Immunology
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Immune Cells
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White Blood Cells
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T Cells
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Medicine and Health Sciences
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Immunology
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Immune Cells
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White Blood Cells
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T Cells
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Biology and life sciences
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Cell biology
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Cellular types
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Animal cells
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Blood cells
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White blood cells
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T cells
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Cytotoxic T cells
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Biology and life sciences
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Cellular types
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Animal cells
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Immune cells
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White blood cells
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T cells
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Cytotoxic T cells
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Immune cells
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White blood cells
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T cells
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Cytotoxic T cells
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Medicine and health sciences
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T cells
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Cytotoxic T cells
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Oncology
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Cancers and Neoplasms
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Regulatory T cells
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Biology and life sciences
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Cellular types
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Animal cells
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Immune cells
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White blood cells
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T cells
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Regulatory T cells
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Biology and life sciences
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Immune cells
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White blood cells
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T cells
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Regulatory T cells
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Medicine and health sciences
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Immunology
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Immune cells
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White blood cells
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T cells
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Regulatory T cells
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Cancers and Neoplasms
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Head and Neck Cancers
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Biology and life sciences
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Cellular types
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Animal cells
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Blood cells
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White blood cells
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NK cells
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Biology and life sciences
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Cell biology
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Cellular types
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Animal cells
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Immune cells
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White blood cells
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NK cells
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Biology and life sciences
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Immunology
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Immune cells
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White blood cells
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NK cells
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Medicine and health sciences
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Immune cells
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White blood cells
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NK cells
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