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      Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis.

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          Abstract

          The benefits of blood pressure lowering treatment for prevention of cardiovascular disease are well established. However, the extent to which these effects differ by baseline blood pressure, presence of comorbidities, or drug class is less clear. We therefore performed a systematic review and meta-analysis to clarify these differences.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          1474-547X
          0140-6736
          Mar 5 2016
          : 387
          : 10022
          Affiliations
          [1 ] The George Institute for Global Health, University of Oxford, Oxford, UK.
          [2 ] The George Institute for Global Health, University of Oxford, Oxford, UK; Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK.
          [3 ] The George Institute for Global Health, University of Oxford, Oxford, UK; King's College Hospital NHS Foundation Trust, London, UK.
          [4 ] Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK.
          [5 ] The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia.
          [6 ] The George Institute for Global Health, University of Oxford, Oxford, UK. Electronic address: kazem.rahimi@georgeinstitute.ox.ac.uk.
          Article
          S0140-6736(15)01225-8
          10.1016/S0140-6736(15)01225-8
          26724178
          a26c9f81-6bed-41c8-8bdc-3ad1a088b0cb
          Copyright © 2016 Elsevier Ltd. All rights reserved.
          History

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