The presented study is the first report of the synthesis of terpyridines in the presence of a nanomagnetic catalyst instead of harmful reagents. Herein, Fe 3O 4@O 2PO 2(CH 2) 2NH 3 +CF 3CO 2 − as a retrievable nanocatalyst with magnetic properties was applied for the multi-component reaction between acetylpyridine derivatives (2 or 3 or 4-isomer), aryl aldehydes and ammonium acetate under conventional heating conditions in the absence of any solvent. The derived terpyridines were obtained with acceptable yields and brief reaction times via a cooperative vinylogous anomeric based oxidation route. Fe 3O 4@O 2PO 2(CH 2) 2NH 3 +CF 3CO 2 − showed a high capability for recovery and reuse in the mentioned reaction.
Fe 3O 4@O 2PO 2(CH 2) 2NH 3 +CF 3CO 2 − as a retrievable nanocatalyst with magnetic properties was applied for the one pot preparation of terpyridines with good yields and short reaction times via a cooperative vinylogous anomeric based oxidation mechanism.