Association of Lipid-Lowering Drugs With Risk of Psoriasis: A Mendelian Randomization Study.

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Abstract

Lipid pathways have been implicated in the pathogenesis of psoriasis, and some lipid-lowering drugs, such as statins, are hypothesized to have disease-modifying properties. However, large population-level studies are scarce, and causal interpretation of results from traditional observational designs is limited by confounding.

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Journal

Journal ID (iso-abbrev): JAMA Dermatol

Title: JAMA dermatology

Publisher: American Medical Association (AMA)

ISSN (Electronic): 2168-6084

ISSN (Print): 2168-6068

Publication date (Electronic): Mar 01 2023

Volume: 159

Issue: 3

Affiliations

[1 ] Centre for Epidemiology Versus Arthritis, Division of Musculoskeletal and Dermatological Science, School of Biological Sciences, Faculty of Biological Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, England.

[2 ] Centre for Dermatology Research, Salford Royal National Health Service Foundation Trust, National Institute for Health and Care Research Manchester Biomedical Research Centre, University of Manchester, Manchester, England.

[3 ] Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, England.

Article

Publisher Item ID: 2800634

DOI: 10.1001/jamadermatol.2022.6051

PMC ID: 9878432

PubMed ID: 36696131

SO-VID: a1454105-005f-4e52-a7cd-9abe42878db9

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