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      Neurological or Psychiatric Disorders After Dengue Fever

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          Abstract

          This cohort study investigates the association between dengue fever and risk of neurological and psychiatric disorders among adults in Taiwan.

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          Most cited references6

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          Nationwide Population Science: Lessons From the Taiwan National Health Insurance Research Database.

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            Neurological Manifestations of Dengue Infection

            Dengue counts among the most commonly encountered arboviral diseases, representing the fastest spreading tropical illness in the world. It is prevalent in 128 countries, and each year >2.5 billion people are at risk of dengue virus infection worldwide. Neurological signs of dengue infection are increasingly reported. In this review, the main neurological complications of dengue virus infection, such as central nervous system (CNS), peripheral nervous system, and ophthalmic complications were discussed according to clinical features, treatment and possible pathogenesis. In addition, neurological complications in children were assessed due to their atypical clinical features. Finally, dengue infection and Japanese encephalitis were compared for pathogenesis and main clinical manifestations.
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              Neurologic complications in dengue virus infection: a prospective cohort study.

              This study aimed to evaluate the incidence and clinical spectrum of neurologic complications, predictors of central and peripheral nervous system involvement, and their outcome in patients with dengue virus infection (DENV).
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                Author and article information

                Journal
                JAMA Netw Open
                JAMA Netw Open
                JAMA Network Open
                American Medical Association
                2574-3805
                7 May 2024
                May 2024
                7 May 2024
                : 7
                : 5
                : e2410075
                Affiliations
                [1 ]Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
                [2 ]Department of Emergency Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
                [3 ]Department of Orthopedics, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan
                [4 ]School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan
                [5 ]Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
                [6 ]Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
                [7 ]Department of Administration, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
                [8 ]Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan
                Author notes
                Article Information
                Accepted for Publication: February 26, 2024.
                Published: May 7, 2024. doi:10.1001/jamanetworkopen.2024.10075
                Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2024 Lin HC et al. JAMA Network Open.
                Corresponding Authors: Yao-Shen Chen, MD, Department of Administration, Kaohsiung Veterans General Hospital, Kaohsiung, No.386, Dazhong 1st Rd., Zuoying District, Kaohsiung City 813414, Taiwan ( yschen@ 123456vghks.gov.tw ); Yu-Chung Juan, MD, Department of Neurosurgery, China Medical University Hospital, Taichung, No. 2, Yude Rd., North District, Taichung City 404327, Taiwan ( danny30662@ 123456gmail.com ).
                Author Contributions: Dr Chang had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Drs Lin and Chou contributed equally as first authors in this article.
                Concept and design: Chou, Chiang, Chang, Chen.
                Acquisition, analysis, or interpretation of data: Lin, Chou, Juan.
                Drafting of the manuscript: Lin, Chou, Chiang, Chang.
                Critical review of the manuscript for important intellectual content: Lin, Chou, Chen, Juan.
                Statistical analysis: Chou, Chang, Chen.
                Obtained funding: Lin, Chou.
                Administrative, technical, or material support: Lin, Chou.
                Supervision: Lin, Chen, Juan.
                Conflict of Interest Disclosures: None reported.
                Funding/Support: This work was supported by grants KSVGH-113-117 from Kaohsiung Veterans Hospital and EDAHS110009 from E-Da Hospital.
                Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
                Data Sharing Statement: See the Supplement.
                Additional Contributions: We acknowledge Chang-Bi Wang, PhD (E-Da Hospital), for his assistance in data collection, analysis, and table formatting. We acknowledge I-Ming Jou, PhD (E-Da Hospital.), for his assistance in interpretation of data in draft. These individuals were not compensated for this work.
                Article
                zld240046
                10.1001/jamanetworkopen.2024.10075
                11077384
                38713469
                9f658410-f64b-4a05-bec2-542e9f9b12f3
                Copyright 2024 Lin HC et al. JAMA Network Open.

                This is an open access article distributed under the terms of the CC-BY License.

                History
                : 23 October 2023
                : 26 February 2024
                Categories
                Research
                Research Letter
                Online Only
                Infectious Diseases

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