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      Gastrografin can be detected in ex vivo biological specimens by dual-energy CT scanning.

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          Abstract

          Dual-energy CT is able to distinguish between materials based on differences in X-ray absorption at different X-ray beam energies. The strong k-edge photoelectric effect of materials with a high atomic number makes this modality ideal for identifying iodine-containing compounds. We aim to evaluate dual-energy CT for the detection of Gastrografin (GG) (diatrizoate, Bayer PLC, Reading, UK) enteric contrast medium and validate the conditions for the measurement in ex vivo samples.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): J Med Imaging Radiat Oncol
          Title: Journal of medical imaging and radiation oncology
          Publisher: Wiley
          ISSN (Electronic): 1754-9485
          ISSN (Print): 1754-9477
          Publication date (Electronic): Oct 2020
          Volume: 64
          Issue: 5
          Affiliations
          [1 ] Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
          [2 ] Department of Surgery, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
          [3 ] Faculty of Medicine, University of Queensland, St Lucia, Brisbane, Queensland, Australia.
          [4 ] St Vincent's Private Hospital Northside, Brisbane, Queensland, Australia.
          [5 ] Department of Medical Imaging, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
          Article
          DOI: 10.1111/1754-9485.13071
          PubMed ID: 32543123
          SO-VID: 9e903087-5ad7-4caa-be12-1a3fa6dae361
          History

          Keywords: iodine measurement,dual-energy CT,biomarker,Gastrografin,iodine quantification
          Data availability:
          Keywords: iodine measurement, dual-energy CT, biomarker, Gastrografin, iodine quantification

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