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      Oxygen in acute and chronic wound healing.

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          Abstract

          Oxygen is a prerequisite for successful wound healing due to the increased demand for reparative processes such as cell proliferation, bacterial defence, angiogenesis and collagen synthesis. Even though the role of oxygen in wound healing is not yet completely understood, many experimental and clinical observations have shown wound healing to be impaired under hypoxia. This article provides an overview on the role of oxygen in wound healing and chronic wound pathogenesis, a brief insight into systemic and topical oxygen treatment, and a discussion of the role of wound tissue oximetry. Thus, the aim is to improve the understanding of the role of oxygen in wound healing and to advance our management of wound patients.

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          Author and article information

          Journal
          Br J Dermatol
          The British journal of dermatology
          Wiley
          1365-2133
          0007-0963
          Aug 2010
          : 163
          : 2
          Affiliations
          [1 ] Department of Dermatology, University Hospital Regensburg, 93042 Regensburg, Germany.
          Article
          BJD9804
          10.1111/j.1365-2133.2010.09804.x
          20394633
          9e5053ad-3fe1-46fc-9aba-8f401ef4ae92
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