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      Predicting COVID-19 vaccine hesitancy in Hong Kong: Vaccine knowledge, risks from coronavirus, and risks and benefits of vaccination

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          Abstract

          Introduction

          Hongkongers have had access to COVID-19 vaccines for about four months, but vaccination rate remains low (34.4% as of 4 July 2021). Given that vaccine uptake is vital, this study aimed to determine how vaccine-hesitant and vaccinated individuals differ. The study also examined why people choose to delay vaccination (within 1 month, within 2 months, within 3 months, 3 months or more).

          Material and Methods

          A population-based online survey ( N = 1654) was conducted between 22 and 30 June 2021, a month after the Hong Kong government announced “Say no to vaccine hesitancy” on its website. All adults aged 18 years and older were eligible to take part. The survey included sociodemographic details, perceived susceptibility to infection, and perceived vaccine efficacy and risks. A series of analyses of covariance was performed to inspect differences among the groups and multiple regression analyses were done to examine factors associated with COVID-19 vaccine hesitancy.

          Results

          With a vaccine hesitancy rate of 30.3%, analyses revealed that sociodemographic factors, party identification and self-reported health status had no effects on the degrees of vaccine hesitancy. While vaccine knowledge, perceived susceptibility to infection, and vaccine efficacy and safety were positive correlates of vaccine uptake, risks from vaccination and vaccine efficacy were positive correlates of vaccine hesitancy.

          Conclusions

          Hesitancy in Hong Kong is more about vaccine efficacy and safety, and less about infection risks. Specifically, respondents expressed concerns about the particular vaccines supplied, especially BioNTech’s efficacy and risks from Sinovac. While higher risk motivates longer preparation for vaccine uptake, higher levels of benefits from BioNTech could reduce hesitancy.

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          Most cited references23

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          Is Open Access

          Vaccine hesitancy: Definition, scope and determinants.

          The SAGE Working Group on Vaccine Hesitancy concluded that vaccine hesitancy refers to delay in acceptance or refusal of vaccination despite availability of vaccination services. Vaccine hesitancy is complex and context specific, varying across time, place and vaccines. It is influenced by factors such as complacency, convenience and confidence. The Working Group retained the term 'vaccine' rather than 'vaccination' hesitancy, although the latter more correctly implies the broader range of immunization concerns, as vaccine hesitancy is the more commonly used term. While high levels of hesitancy lead to low vaccine demand, low levels of hesitancy do not necessarily mean high vaccine demand. The Vaccine Hesitancy Determinants Matrix displays the factors influencing the behavioral decision to accept, delay or reject some or all vaccines under three categories: contextual, individual and group, and vaccine/vaccination-specific influences.
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            High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2

            Severe acute respiratory syndrome coronavirus 2 is the causative agent of the ongoing coronavirus disease pandemic. Initial estimates of the early dynamics of the outbreak in Wuhan, China, suggested a doubling time of the number of infected persons of 6–7 days and a basic reproductive number (R0) of 2.2–2.7. We collected extensive individual case reports across China and estimated key epidemiologic parameters, including the incubation period (4.2 days). We then designed 2 mathematical modeling approaches to infer the outbreak dynamics in Wuhan by using high-resolution domestic travel and infection data. Results show that the doubling time early in the epidemic in Wuhan was 2.3–3.3 days. Assuming a serial interval of 6–9 days, we calculated a median R0 value of 5.7 (95% CI 3.8–8.9). We further show that active surveillance, contact tracing, quarantine, and early strong social distancing efforts are needed to stop transmission of the virus.
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              Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: a systematic review of published literature, 2007-2012.

              Vaccine "hesitancy" is an emerging term in the literature and discourse on vaccine decision-making and determinants of vaccine acceptance. It recognizes a continuum between the domains of vaccine acceptance and vaccine refusal and de-polarizes previous characterization of individuals and groups as either anti-vaccine or pro-vaccine. The primary aims of this systematic review are to: 1) identify research on vaccine hesitancy; 2) identify determinants of vaccine hesitancy in different settings including its context-specific causes, its expression and its impact; and 3) inform the development of a model for assessing determinants of vaccine hesitancy in different settings as proposed by the Strategic Advisory Group of Experts Working Group (SAGE WG) for dealing with vaccine hesitancy. A broad search strategy, built to capture multiple dimensions of public trust, confidence and hesitancy around vaccines, was applied across multiple databases. Peer-reviewed studies were selected for inclusion if they focused on childhood vaccines [≤ 7 years of age], used multivariate analyses, and were published between January 2007 and November 2012. Our results show a variety of factors as being associated with vaccine hesitancy but they do not allow for a complete classification and confirmation of their independent and relative strength of influence. Determinants of vaccine hesitancy are complex and context-specific - varying across time, place and vaccines. Copyright © 2014 Elsevier Ltd. All rights reserved.
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                Author and article information

                Journal
                Vaccine X
                Vaccine X
                Vaccine: X
                Published by Elsevier Ltd.
                2590-1362
                29 April 2022
                August 2022
                29 April 2022
                : 11
                : 100164
                Affiliations
                Department of Communication Studies, Hong Kong Baptist University, Kowloon Tong, Hong Kong
                Author notes
                [* ]Address: Room 916, 9/F, Lee Shau Kee Communication and Visual Arts Building, Baptist University Road Campus, Hong Kong Baptist University, 5 Hereford Road, Kowloon Tong, Hong Kong.
                Article
                S2590-1362(22)00024-9 100164
                10.1016/j.jvacx.2022.100164
                9077988
                35573268
                9dfbf0c6-9cc4-4d40-b5ef-97e668e759e6
                © 2022 Published by Elsevier Ltd.

                Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

                History
                : 13 July 2021
                : 6 October 2021
                : 25 April 2022
                Categories
                Article

                covid-19,vaccines,hesitancy,risks assessment,hong kong,covid-19, coronaricus disease 2019

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