Differences in fatty acid metabolic disorder between ischemic myocardium and doxorubicin-induced myocardial damage: assessment using BMIPP dynamic SPECT with analysis by the Rutland method.

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Abstract

Dynamic myocardial SPECT data acquired with 15-(123)I-(p-iodophenyl)-3-(R,S)-methylpentadecanoic acid (BMIPP) were analyzed by the Rutland method. The relative time-activity curves generated from dynamic SPECT in normal control subjects were compared with similar curves from patients with established ischemic heart disease (IHD) and doxorubicin-induced myocardial damage (DxMD). Comparison of such time-activity curves may provide some indirect information concerning qualitative differences in BMIPP metabolism.

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Journal

Journal ID (iso-abbrev): J Nucl Med

Title: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

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ISSN: 0161-5505

ISSN (Print): 0161-5505

Publication date (Electronic): Oct 2002

Volume: 43

Issue: 10

Affiliations

[1 ] Department of Radiology, Matsusaka Central Hospital, Mie, Japan. kakuya@clin.medic.mie-u.ac.jp

Article

PubMed ID: 12368365

SO-VID: 9c6a15d8-6d88-43cf-831e-f122573af46b

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